Title
Author
DOI
Article Type
Special Issue
Volume
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A case of vulval basosquamous basal cell carcinoma with possible pelvic lymph node metastases
1Department of Obstetrics and Gynaecology, Mid and South Essex NHS Foundation Trust, Prittlewell Chase, SS0 0RY Southend-on-Sea, UK
2Department of Plastic Surgery, Mid and South Essex NHS Foundation Trust, Prittlewell Chase, SS0 0RY Southend-on-Sea, UK
3Department of Radiology, Mid and South Essex NHS Foundation Trust, Prittlewell Chase, SS0 0RY Southend-on-Sea, UK
4Department of Pathology, Mid and South Essex NHS Foundation Trust, Prittlewell Chase, SS0 0RY Southend-on-Sea, UK
5Department of Oncology, Mid and South Essex NHS Foundation Trust, Prittlewell Chase, SS0 0RY Southend-on-Sea, UK
DOI: 10.31083/j.ejgo4204124 Vol.42,Issue 4,August 2021 pp.817-823
Submitted: 11 February 2021 Accepted: 22 April 2021
Published: 15 August 2021
*Corresponding Author(s): Noemi J Hughes E-mail: noemihughes@doctors.org.uk
Background: Basal cell carcinoma (BCC) is the most common cutaneous neoplasm. It is most often a locally invasive tumour and rarely affects the vulva. Distant spread of BCC is rarer still and there are few cases reported of metastatic vulval primary tumours. Basosquamous carcinoma is regarded as a high-risk variant of BCC and its behaviour is unpredictable. Though more aggressive, it tends to grow locally rather than spread to lymph nodes as seen in squamous cell carcinoma (SCC). Case: We present a case of a basosquamous BCC arising in the vulva with involvement of the external and common iliac lymph nodes. Conclusion: Metastatic BCC has a poor prognosis and there are no definitive guidelines for its investigation or management. We recommend staging with imaging and potentially lymph node dissection in patients with large lesions involving underlying structures or aggressive histology.
Vulval cancer; Metastatic basal cell carcinoma; Gynaecology oncology; Staging radiology
Noemi J Hughes,Konstantinos M Ntalianis,Khalil Razvi,Mary Morgan,Sherief Marzouk,Maryse Sundaresan,Krishnaswamy S Madhavan,Sidath H Liyanage. A case of vulval basosquamous basal cell carcinoma with possible pelvic lymph node metastases. European Journal of Gynaecological Oncology. 2021. 42(4);817-823.
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