Unraveling the mystery of uterine cotyledonoid dissecting leiomyoma: a case report

Cotyledonoid Dissecting Leiomyoma is a rare condition that can be presented as a malignant tumor and may be challenging to diagnose for gynecologists, radiologists and pathologists. We report a case of this tumor in a 40-year-old woman better to understand its clinical, surgical and pathologic features and explore its diagnostic and treatment aspects. The patient presented with chronic suprapubic pain for over two years, while the clinical, radiological and surgical findings were worrisome. In our case, the histopathological examination did not reveal any malignant features, confirming the benign nature of CDL. Positive staining for desmin and caldesmon confirmed the smooth muscle nature of this tumor, and the absence of coagulative tumor cell necrosis, nuclear atypia and absence of increased mitotic activity ruled out leiomyosarcoma. This rare case report provides distinctive patient’s clinical presentation, diagnostic workup, surgical intervention and histopathological findings.

Cotyledonoid dissecting leiomyoma; Cotyledonoid; Dissecting; Leiomyoma; Uterine tumor; Desmin; H-Caldesmon; Case report

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