Leiomyosarcoma of the broad ligament: a case report with CT and MRI images

Primary leiomyosarcoma of the broad ligament is a very rare and highly malignant gynecological tumor. The authors report a 61-year-old postmenopausal woman with signs and symptoms of malignant ovarian tumor. Preoperative magnetic resonance imaging (MRI) was interpreted as being suspicious for malignant tumors, such as an ovarian cancer or a leiomyosarcoma of the broad ligament, so laparotomy was performed. Macroscopically, the tumor was revealed with a 18×13.7×9.5 cm degenerated, multiple cystic part and solid whitish part arising from broad ligament which on histopathology proved to be leiomyosarcoma. To the best of the authors’ knowledge, primary leiomyosarcoma of the broad ligament has been documented in 21 reports or so, and no imaging findings are available. Here the authors present the MRI findings of primary leiomyosarcoma of the broad ligament.

Leiomyosarcoma; Broad ligment; Pelvic tumor; MRI.

[1] Kolusari A., Ugurluer G., Kosem M., Kurdoglu M., Yildizhan R., Adali E.: “Leiomyosarcoma of the broadligament: a case report and review of the literature”. Eur. J. Gynaecol. Oncol., 2009, 30, 332- 4.

[2] Clarke B.A., Rahimi K., Chetty R.: “Leiomyosarcoma of the broad ligament with osteoclast-like giant cells and rhabdoid cells”. Int. J. Gynecol. Pathol., 2010, 29, 432.

[3] Bousfina N., Saadi H., Errarhay S.: “Leiomyosarcoma of the broad ligament: a case report and the review of the literature”. Anatol. J. Obstet. Gynecol., 2011, 2, 2.

[4] Menn K.A., Qin L., Fedoriw G.D., Gillette M.E., McCarthy S.: “Uterus-Like Mass: MRI appearance of a very rare entity”. J. Magn. Reson. Imaging, 2007, 26, 162.

[5] Hensley M.L., Blessing J.A., Mannel R., Rose P.G.: “Fixed-dose rate gemcitabine plus docetaxel as Wrst-line therapy for metastatic uterine leiomyosarcoma: a Gynecologic Oncology Group phase II trial”. Gynecol. Oncol., 2008, 109, 329.

[6] Gardner G.H., Greene R.R., Peckham R.: “Tumors of the broadligament”. Am. J. Obstet. Gynecol., 1957, 73, 536.

[7] Cheng W.F., Lin H.H., Chen C.K., Chang D.Y., Huang S.C.: “Leiomyosarcoma of the broad ligament: a case report and literature review”. Gynecol. Oncol., 1995, 56, 85.

[8] Berchuck A., Rubin SC., Hoskins WJ., Saigo PE., Pierce VK., Lewis JL Jr.: “Treatment of uterine leiomyosarcoma”. Obstet. Gynecol., 1988, 71, 845.

[9] Ben Amara F., Jouini H., Nasr M., Malek M., Neji K., Reziga H. et al.: “Primary leiomyosarcoma of broad ligament”. Tunis Med., 2007, 85, 591.

[10] Sapillane A.J., Thomas J.M.: “Gynaecological presentation of retroperitoneal tumours”. BJOG, 2000, 107, 170.