Evaluation of depth of myometrial invasion by magnetic resonance imaging in patients with endometrial carcinoma

Aims: The aim of this study was to evaluate clinical accuracy of magnetic resonance imaging (MRI) staging of myometrial invasion in patients with endometrial carcinoma. Methods: The study group consisted of 37 women with endometrial carcinoma who underwent preoperative workup, including MRI, and surgical staging at Goztepe Training Hospital, Istanbul, Turkey. We collected clinical, MRI, surgical and histopathological data of the study subjects from patients' charts. Results: The mean patient age was 57 years (range 39-76 years). Of the subjects, 32 (86.5%) had endometrioid carcinoma. After histopathological evaluation, we found that four (10.8%) patients had no myometrial invasion, 14 (37.8%) had superficial myometrial invasion, and 19 (51.3%) had deep myometrial invasion. Overall, the accuracy of MRI staging increased in accordance with the increase of surgical stage of endometrial carcinoma. Overall, clinical success of MRI staging was higher in patients with deep myometrial invasion. Conclusion: The accuracy of MRI to depict the depth of myometrial invasion increases in accordance with surgical stage in patients with endometrial cancer. The combination of MRI and clinical findings may be helpful in determining the extent of surgery.

Endometrial cancer; Magnetic resonance imaging; Myometrial invasion

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