Article Data

  • Views 234
  • Dowloads 136

Original Research

Open Access

Rare case of an ovarian monodermal teratoma with functional stroma and extensive ovarian decidualization in a 74-year-old woman

  • E. Vouza1
  • Ch. Dastamani1
  • Ch. Iavazzo2
  • K. Bakalianou2
  • D. Hasiakos2
  • A. Kondi-Pafiti1,*,

1Pathology Laboratory, University of Athens, Aretaieion Hospital, Athens, Greece

22nd Department of Obstetrics and Gynecology, University of Athens, Aretaieion Hospital, Athens, Greece

DOI: 10.12892/ejgo201102243 Vol.32,Issue 2,March 2011 pp.243-245

Published: 10 March 2011

*Corresponding Author(s): A. Kondi-Pafiti E-mail: akondi@med.uoa.gr

Abstract

We present the clinicopathological findings of a rare case of a monodermal teratoma of the right ovary with functional ovarian stroma and extensive decidualization in a 74-year-old woman. The patient presented with vaginal bleeding. Ultrasound scan revealed a pelvic mass measuring 9.5 cm in the lower right abdomen. A right oophorectomy was performed. The tumor was cystic and multilocular filled with colloid material. Histological examination revealed follicles of thyroid type, and stromal clusters of fusiform or polygonal cells were found in the stroma. An extensive decidual reaction was observed. Morphological and immunohistochemical examination of the tumor revealed cystic struma ovarii with functional ovarian stroma and ectopic decidua. Total abdominal hysterectomy with oophorectomy was performed. A benign endometrial polyp, proliferative endometrium, two fibroids, and an ovarian cyst were observed.

Keywords

Struma ovarii; Ovarian stroma; Decidua; Ovary

Cite and Share

E. Vouza,Ch. Dastamani,Ch. Iavazzo,K. Bakalianou,D. Hasiakos,A. Kondi-Pafiti. Rare case of an ovarian monodermal teratoma with functional stroma and extensive ovarian decidualization in a 74-year-old woman. European Journal of Gynaecological Oncology. 2011. 32(2);243-245.

References

[1] Szyfelbein W.M., Young R.H., Scully R.E.: “Cystic struma ovarii: A frequently unrecognized tumor. A report of 20 cases”. Am.J. Surg. Pathol., 1994, 18, 785.

[2] Iavazzo C., Vorgias G., Psarrou A., Lekka I., Katsoulis M.: “Late struma ovarii diagnosis many years after total thyroidectomy.A rare entity”. J. Buon., 2008, 13, 573.

[3] Rutgers J.L., Scully R.E.: “Functioning ovarian tumors with peripheral steroid cell proliferation: A report of 24 cases”. Int. J. Gynecol. Pathol., 1986, 5, 319.

[4] Guida M., Mandato V.D., Di Spiezio Sardo A., Di Carlo C., Giordano E., Nappi C.: “Coexistence of Graves’ disease and benign struma ovarii in a patient with marked ascites and elevated CA-125 levels”. J. Endocrinol. Invest., 2005, 28, 827.

[5] Bokhari A., Rosenfeld G.S., Cracchiolo B., Heller D.S.: “Cystic struma ovarii presenting with ascites and an elevated CA-125 level. A case report”. J. Reprod. Med., 2003, 48, 52.

[6] McCluggage W.G., Young R.H.: “Immunohistochemistry as a diagnostic aid in the evaluation of ovarian tumors”. Semin. Diagn. Pathol., 2005, 22, 3.

[7] Clement P.B., Young R.H.: “Tumor-like lesions of the ovary”. In: Clement P.B., Young R.H (eds.). Atlas of Gynecologic Oncology, 2nd edition, Philadelphia, W.B.Saunders, 2008, 294.

[8] Zhang X., Axiotis C.: “Thyroid-type carcinoma of struma ovarii”. Arch. Pathol. Lab. Med., 2010, 134, 786.

[9] Szyfelbein W.M., Young R.H., Scully R.E.: “Struma ovarii simulating ovarian tumors of other types. A report of 30 cases”. Am. J. Surg. Pathol., 1995, 19, 21.

[10] Tokunada H., Akahira J., Suzuki T.: “Ovarian epithelial carcinoma with estrogen-producing stroma”. Pathol. Internat., 2007, 57, 285.

[11] Hayasaka T., Nakahara K., Kojimahara T.: “Endometrioid adenocarcinoma with a functioning stroma”. Obstet. Gynecol. Res.,2007, 33, 381.

[12] Mils S., Carter D., Greenson J., Reuter V.E., Stoler M.H.: “Sternberg’s Diagnostic Surgical Pathology”. 5th edition, Lippincott, Williams & Wilkens, Philadelphia, 2010, 2333.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top