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Prolonged survival after episiotomy recurrence of cervical cancer complicating pregnancy
1Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202 USA
2Division of Gynecologic Oncology, Indiana University School of Medicine, Indianapolis, IN 46202 USA
*Corresponding Author(s): P.A.S. Johnstone E-mail: pajohnst@iupui.edu
Background: We report a case of recurrent cervical cancer in an episiotomy scar and the late treatment-related sequelae. Case: Cervical cancer was diagnosed following a vaginal delivery, and was treated with surgery and radiotherapy. The patient developed a recurrence in her episiotomy scar, and was treated with chemoradiation. She remains without evidence of disease ten years later. Conclusion: Successful treatment of recurrent cervical cancer with chemoradiation is possible, but may be associated with significant normal tissue toxicity.
Episiotomy; Cervical cancer; Pregnancy complication; Surgery; Radiation therapy
I. Hafeez,B.D. Lawenda,J.M. Schilder,P.A.S. Johnstone. Prolonged survival after episiotomy recurrence of cervical cancer complicating pregnancy. European Journal of Gynaecological Oncology. 2011. 32(2);211-213.
[1] Wingo P.A., Tong T, Bolden S.: “Cancer statistics”. CA Cancer J. Clin., 1995, 45, 8.
[2] Duggan B., Muderspach L.I., Roman L.D., Curtin J.P., d’Alaing G. 3rd, Morrow C.P.: “Cervical cancer in pregnancy: reporting on planned delay in therapy”. Obstet. Gynecol., 1993, 82, 598.
[3] Burgess S.P., Waymont B.: “Implantation of a cervical carcinoma in an episiotomy site. Case report”. Br. J. Obstet. Gynaecol., 1987, 94, 598.
[4] Copeland L.J., Saul P.B., Sneige N.: “Cervical adenocarcinoma: tumor implantation in the episiotomy sites of two patients”. Gynecol. Oncol., 1987, 28, 230.
[5] Gordon A.N., Jensen R., Jones H.W. 3rd: “Squamous carcinoma of the cervix complicating pregnancy: recurrence in episiotomy after vaginal delivery”. Obstet. Gynecol., 1989, 73, 850.
[6] Van Dam P.A., Irvine L., Lowe D.G., Fisher C., Barton D.P., Shepherd J.H.: “Carcinoma in episiotomy scars”. Gynecol. Oncol., 1992, 44, 96.
[7] Khalil A.M., Khatib R.A., Mufarrij A.A., Tawil A.N., Issa P.Y.: “Squamous cell carcinoma of the cervix implanting in the episiotomy site”. Gynecol. Oncol., 1993, 51, 408.
[8] Cliby W.A., Dodson M.K., Podratz K.C.: “Cervical cancer complicated by pregnancy: episiotomy site recurrences following vaginal delivery”. Obstet. Gynecol., 1994, 84, 179.
[9] Van den Broek N.R., Lopez A.D., Ansink A., Monaghan J.M.: “‘Microinvasive’ adenocarcinoma of the cervix implanting in anepisiotomy scar”. Gynecol. Oncol., 1995, 59, 297.
[10] Goldman N.A., Goldberg G.I.: “Late recurrence of squamous cell cervical cancer in an episiotomy site after vaginal delivery”. Obstet. Gynecol., 1003, 101, 1127.
[11] Amanie J., Pearcey R.G., Honore L., Sloboda R.: “Metastatic adenocarcinoma of the cervix ina delivery-induced traumatic lower vaginal tear”. Gynecol. Oncol., 2005, 96, 857.
[12] Heron D.E., Axtel A., Gerszten K.: “Villoglandular adenocarcinoma of the cervix recurrent in an episiotomy scar: a case report in a 32- year-old female”. Int. J. Gynecol. Cancer, 2005, 15, 366.
[13] Baloglu A., Uysal D., Aslan N., Yigit S.: “Advanced stage of cervical carcinoma undiagnosed during antenatal period in termpregnancy and concomitant metastasis on episiotomy scar during delivery: a case report and review of the literature”. Int. J. Gynecol. Cancer, 2007, 17, 1155.
[14] Neumann G., Rasmussen K.L., Petersen L.K.: “Cervical adenosquamous carcinoma: tumor implantation in an episiotomy scar”. Obstet. Gynecol., 2007, 110, 467.
[15] Williams T.J., Brack C.B.: “Carcinoma of the cervix in pregnancy”. Cancer, 1964, 17, 1486.
[16] Greenlee R.M., Chervenak F.A., Tovell H.M.: “Incisional recurrence of a cervical carcinoma. Report of a case”. JAMA, 1981, 246, 69.
[17] Hopkins M.P., Morley G.W.: “The prognosis and management of cervical cancer associated with pregnancy”. Obstet. Gynecol., 1992, 80, 9.
[18] Sood A.K., Sorosky J.I.: “Cervical cancer diagnosed shortly after pregnancy: prognostic variable and delivery routes”. Obstet. Gynecol., 2000, 95, 832.
[19] Dupree M.T., Kitely R.A., Weismantle K., Panos R., Johnstone P.A.S.: “Radiation therapy for treatment of Bowen’s disease: lessons for lesions of the lower extremity”. J. Am. Acad. Dermatol., 2001, 45, 401.
[20] Hacker N.F., Berek J.S., Lagasse L.D., Charles E.H.: “Carcinoma of the cervix associated with pregnancy”. Obstet. Gynecol., 1982, 28, 230.
[21] Mikuta J.J.: “Invasive carcinoma of the cervix in pregnancy”. South Med. J., 1967, 60, 823.
[22] Ra K.: “Factors affecting the prognosis of cancer of the cervix in pregnancy”. Am. J. Obstet. Gynecol., 1961, 82, 45.
[23] Pradhan S., Asthana A.K., Sharan G.K.: “Recurrence of carcinoma cervix in the scar of previous cesarean section: a case report”. Int. J. Gynecol. Cancer, 2006, 16, 900.
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