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Original Research

Open Access

Primary malignant melanoma of the vagina

  • N. Takai1,*,
  • N. Kai2
  • Y. Hirata3
  • K. Kashima4
  • H. Narahara1

1Department of Obstetrics and Gynecology, Japan

2Department of Dermatology, Japan

3Department of Urology, Japan

4Department of Pathology, Oita University Faculty of Medicine, Oita, Japan

DOI: 10.12892/ejgo200805558 Vol.29,Issue 5,September 2008 pp.558-559

Published: 10 September 2008

*Corresponding Author(s): N. Takai E-mail:

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Abstract

Malignant melanoma originating in the vagina is considered extremely rare and has a very poor prognosis. We report a case of a 70-year-old woman with primary malignant melanoma of the vagina. and discuss the importance of prognostic factors and the efficacy of adjuvant chemotherapy.

Cite and Share

N. Takai,N. Kai,Y. Hirata,K. Kashima,H. Narahara. Primary malignant melanoma of the vagina. European Journal of Gynaecological Oncology. 2008. 29(5);558-559.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200805558

References

[1] Buchanan D.J., Schlaerth J., Kurosaki T.: “Primary vaginal melanoma: 13-year disease-free survival after wide local excision and review of recent literature”. Am. J. Obstet. Gynecol., 1998, 178, 1177.

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[4] Petru E., Nagele K., Czerwenka K., Graf A.H., Lax S., Bauer M. et al.: “Primary vaginal melanoma of the vagina: long-term remission following radiation therapy”. Gynecol. Oncol., 1998, 70, 23.

[5] Chung A.F., Casey M.J., Flannery J.T., Woodruff J.M., Lewis J.L.: “Malignant melanoma of the vagina-report of 19 cases”. Obstet. Gynecol., 1980, 55, 720.

[6] Rodier J.F., Janser J.C., David E., Routiot T., Ott G..: “Radiopharmaceuticalguided surgery in primary malignant melanoma of the vagina”. Gynecol. Oncol., 1999, 75, 308.

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[8] Moschos S.J., Edington H.D., Land S.R., Rao U.N., Jukic D., Shipe-Spotloe J. et al.: “Neoadjuvant treatment of regional Stage IIIB melanoma with high-dose interferon alfa-2b induces objective tumor regression in association with modulation of tumor infiltrating host cellular immune responses”. J. Clin. Oncol., 2006, 24, 3164.

[9] Eisen T., Ahmad T., Flaherty K.T., Gore M., Kaye S., Marais R. et al.: “Sorafenib in advanced melanoma: a phase II randomised discontinuation trial analysis”. Br. J. Cancer, 2006, 95, 581.

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