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Original Research

Open Access

Malignant transformation of uterine leiomyomata

  • U. Indraccolo1,*,
  • G. Luchetti2
  • S.R. Indraccolo1

1Department of Surgical Sciences, Institution of Obstetrics and Gynecology, University of Foggia, Italy

2Service of Echography, Casa di Cura Dott. Marchetti, Macerata, Italy

3Department of Gynecology, Perinatology and Child Welfare, II Faculty of Medicine and Surgery, “La Sapienza” University of Rome, Italy

DOI: 10.12892/ejgo200805543 Vol.29,Issue 5,September 2008 pp.543-544

Published: 10 September 2008

*Corresponding Author(s): U. Indraccolo E-mail: ugo.indraccolo@libero.it

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Abstract

The malignant transformation of a uterine leiomyoma is still debated and, if it occurs, it is very rare. The case of a patient affected by three small leiomyomas, monitored by the same gynecologist over the years is described. Two of these leiomyomas were transformed into leiomyosarcoma after menopause and the patient died despite receiving therapy. The case reported here is meant to underline the need to keep all uterine myomas in check since the transition into leiomyosarcomas may occur with an evolution over a time period which has not been established so far.

Keywords

Leiomysarcoma; Uterus; Leiomyoma

Cite and Share

U. Indraccolo,G. Luchetti,S.R. Indraccolo. Malignant transformation of uterine leiomyomata. European Journal of Gynaecological Oncology. 2008. 29(5);543-544.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200805543

References

[1] Schwartz P.E., Kelly M.G.: “Malignant transformation of myomas: myth or reality?”. Obstet. Gynecol. Clin. North. Am., 2006, 33, 183.

[2] Esposito N.N., Hunt J.L., Bakker A., Jones M.W.: “Analysis of allelic loss as an adiuvant tool evaluation of malignancy in uterine smooth muscle tumors”. Am. J. Surg. Pathol., 2006, 30, 97.

[3] Rotmensch J., Boenyak S., Montag A.: “Malignant transition of uterine leiomyomata”. Int. J. Gynaecol. Obstet., 1993, 42, 47.

[4] Mittal K., Popiolek D., Demopulos R.I.: “Uterine myxoid leiomyosarcoma arising within a leiomyoma”. Hum. Pathol., 2000, 31, 398.

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