Article Data

  • Views 1169
  • Dowloads 102

Original Research

Open Access

Metastatic spread of gynaecological neoplasms to the adrenal gland: case reports with a review of the literature

  • M. Baron1,*,
  • L. Hamou1
  • S. Laberge2
  • F. Callonnec3
  • A. Tielmans4
  • P. Dessogne1

1Department of Surgery, France

2Department of Pathology, France

3Department of Radiology, Becquerel Cancer Center, France

4Department of Endocrinology, Rouen University Hospital, Rouen, France

DOI: 10.12892/ejgo200805523 Vol.29,Issue 5,September 2008 pp.523-526

Published: 10 September 2008

*Corresponding Author(s): M. Baron E-mail: marc.baron@rouen.fnclcc.fr

Abstract

Metastatic involvement of the adrenal glands due to gynaecological neoplasms is a relatively rare condition. The aim of our Study was to present four cases of metastases to the adrenal gland due to endometrial adenocarcinoma, ovarian and cervical cancer. These cases are correlated with a review of the literature. CT scan and MRI have been previously used in an attempt to define the nature of the adrenal mass but this approach is of limited value in diagnosis. Image-guided pathological confirmation of an adrenal lesion may significantly change the staging or management of the primary neoplasm. The authors suggest that isolated adrenal metastasis should be routinely considered for surgical management.

Keywords

Adrenal metastasis; Endometrial adenocarcinoma; Ovarian cancer; Cervical cancer; Vulvar cancer

Cite and Share

M. Baron,L. Hamou,S. Laberge,F. Callonnec,A. Tielmans,P. Dessogne. Metastatic spread of gynaecological neoplasms to the adrenal gland: case reports with a review of the literature. European Journal of Gynaecological Oncology. 2008. 29(5);523-526.

References

[1] Kim S.H., Brennan M.F., Russo P., Burt M.E., Coit D.G.: “The role of surgery in the treatment of clinically isolated adrenal metastasis”. Cancer, 1998, 82, 389.

[2] Abrams H.L., Spiro R., Goldstein N.: “Metastases in carcinoma: analysis of 1000 autopsied cases”. Cancer, 1950, 3, 74.

[3] Gross B.H., Goldberg H.I., Moss A.A., Harter L.P.: “CT demonstration and guided aspiration of unusual adrenal metastasis”. J. Computer Assist. Tomograp., 1983, 7, 98.

[4] Katz R.L., Shirkhoda A.: “Diagnostic approach to incidental adrenal nodules in the cancer patient. Results of a clinical, radiologic and fine-needle aspiration study”. Cancer, 1985, 55, 1995.

[5] Seidenwurm D.J., Elmer E.B., Kaplan L.M., Williams E.K., Morris D.G., Hoffman A.R.: “Metastases to the adrenal glands and the development of Addison’s disease”. Cancer, 1984, 54, 552.

[6] Yun M., Kim W., Alnafisi N., Lacorte L., Jang S., Alavi A.: “18FFDG PET in characterizing adrenal lesions detected on CT or MRI”. J. Nucl. Med., 2001, 12, 1795.

[7] Welch T.J., Sheedy P.F., Stephens D.H., Johnson C.M., Swensen S.J.: “Percutaneous adrenal biopsy: review of a 10-year experience”. Radiology, 1994, 193, 341.

[8] Sarela A.I., Murphy I., Coit D.G., Conlon K.C.: “Metastasis to the adrenal gland: the emerging role of laparoscopic surgery”. Ann. Surg. Oncol., 2003, 10, 1191.

[9] Drescher C.W., Hopkins M.P., Roberts J.A.: “Comparison of the pattern of metastatic spread of squamous cell cancer and adenocarcinoma of the uterine cervix”. Gynecol. Oncol., 1989, 33, 340.

[10] Dvoretsky P.M., Richards K.A., Angel C., Rabinowitz L., Stoler M.H., Beecham J.B. et al.: “Distribution of disease at autopsy in 100 women with ovarian cancer”. Hum. Pathol., 1988, 19, 57.

[11] Einat S., Amir D., Silvia M., Moshe I.: “Successful laparoscopic removal of a solitary adrenal metastasis from ovarian carcinoma : a case report”. Gynecol. Oncol., 2002, 85, 201.

[12] Patlas M., O’Malley M.E., Chapman W.: “Adrenal metastasis from ovarian carcinoma”. AJR Am. J. Roentgenol., 2004, 183, 1711.

[13] Redman B.G., Pazdur R., Zingas A.P., Loredo R.: “Prospective evaluation of adrenal insufficiency in patients with adrenal metastasis”. Cancer, 1987, 60, 103.

[14] Nakano K.K., Schoene W.C.: “Endometrial carcinoma with a predominant clear-cell pattern with metastases to the adrenal, posterior mediastinum, and brain”. Am. J. Obstet. Gynecol., 1975, 122, 529.

Abstracted / indexed in

Web of Science (WOS) (On Hold)

Journal Citation Reports/Science Edition

Google Scholar

JournalSeek

Submission Turnaround Time

Top