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Stage 1B cervical cancer in a pregnant woman at 25 weeks of gestation
1Department of Obstetrics and Gynecology, Spain
2Department of Pathology, Spain
3Department of Radiological Diagnostics Hospital Sant Joan de Déu, University of Barcelona, Esplugues, Barcelona, Spain
*Corresponding Author(s): E. González Bosquet E-mail: egonzalezb@hsjdbcn.org
Cervical cancer associated with pregnancy is rare (0.05%), although it is the most frequently diagnosed malignancy in pregnant women. We present the case of a 28-year-old woman at 25 weeks of gestation diagnosed with Stage 1 B cervical cancer. Treatment was delayed until fetal maturity, and an elective cesarean section was performed at 33 weeks' gestation, followed by a total hysterectomy preserving the ovaries, and a pelvic lymphadenectomy. A review of the literature on the treatment of cervical cancer during pregnancy relevant to the case described is also presented.
Cervical cancer; Pregnancy; Hysterectomy; Delay in treatment
E. González Bosquet,A. Castillo,M. Medina,M. Suñol,A. Capdevila,J.M. Lailla. Stage 1B cervical cancer in a pregnant woman at 25 weeks of gestation. European Journal of Gynaecological Oncology. 2008. 29(3);276-279.
[1] Caluwaerts S., Van Calsteren K., Mertens L., Lagae L., Moerman P., Hanssens M. et al.: “Neoadjuvant chemotherapy followed by radical hysterectomy for invasive cervical cancer diagnosed during pregnancy: report of a case and review of the literature”. Int. J. Gynecol. Cancer, 2006, 16, 905.
[2] Lutz Mh, Underwood P.B. Jr, Rozier J.C., Putney F.W.: “Genital malignancy in pregnancy”. Am. J. Obstet. Gynecol., 1977, 129, 536.
[3] Williams S.F., Bitran J.D.: “Cancer and pregnancy”. Clin. Perinatol., 1985, 12, 609.
[4] Nieminen U., Remes N.: “Malignancy during pregnancy”. Acta Obstet. Gynecol. Scand., 1970, 49, 315.
[5] Hacker N.F., Berek J.S., Lagasse L.D., Elsworth C.H., Savage E.W., Moore J.G.: “Carcinoma of the cervix associated with pregnancy”. Obstet. Gynecol., 1982, 59, 735.
[6] van der Vange N., Weverling G.J., Ketting B.W., Ankum W.M., Samlal R., Lammes F.B.: “The prognosis of cervical cancer associated with pregnancy: a matched cohort study”. Obstet. Gynecol., 1995, 85, 1022.
[7] Hopkins M.P., Morley G.W.: “The prognosis and management of cervical cancer with pregnancy”. Obstet. Gynecol., 1992, 80, 9.
[8] Zemlickis D., Lishner M., Degendorfer P., Panzarella T., Sutcliffe S.B., Koren G.: “Maternal and fetal outcome after invasive cervical cancer in pregnancy”. J. Clin. Oncol., 1991, 9, 1956.
[9] Dudan R.C., Yon J.L., Ford J.H., Averette H.E.: “Carcinoma of the cervix and pregnancy”. Gynecol. Oncol., 1973, 1, 283.
[10] van Vliet W., van Loon A.J., ten Hoor K.A., Boonstra H.: “Cervical carcinoma during pregnancy: outcome of planned delay in treatment”. Eur. J. Obstet. Gynecol. Reprod. Biol., 1998, 79, 153.
[11] Bosch F.X., Lorincz A., Muñoz N., Meijer C.J.L.M., Shah K.V.: “The causal relation between human papilloma virus and cervical cancer”. J. Clin. Pathol., 2002, 55, 244.
[12] Duggan B., Muderspach L.I., Roman L.D., Curtin J.P., d’Ablaing III, Morrow C.P.: “Cervical cancer in pregnancy: reporting on planned delay in therapy”. Obstet. Gynecol., 1993, 82, 598.
[13] Robova H., Rob L., Pluta M., Kacirek J., Halaska M. Jr., Strnad P., Schlegerova D.: “Squamous intraepithelial lesion-microinvasive carcinoma of the cervix during pregnancy”. Eur. J. Gynaecol. Oncol., 2005, 26, 611.
[14] Traen K., Svane D., Kryger-Baggesen N., Bertelsen K., Mogensen O.: “Stage Ib cervical cancer during pregnancy: planned delay in treatment-case report”. Eur. J. Gynaecol. Oncol., 2006, 27, 615.
[15] Nguyen C., Montz F.J., Bristow R.E.: “Management of Stage I cervical cancer in pregnancy”. Obstet. Gynecol. Surv., 2000, 55, 633.
[16] Panek G., Zielinski J., Bidzinski M.: “Results of treating Stage IB invasive carcinoma of the cervix complicating pregnancy”. Ginekol. Pol., 2002, 73, 24.
[17] Bader A.A., Petru E., Winter R.: “Long-term follow-up after neoadjuvant chemotherapy for high-risk cervical cancer during pregnancy”. Gynecol. Oncol., 2007, 105, 269.
[18] Stan C., Megevand E., Irion O., Wang C., Bruchim I., Petignat P.: “Cervical cancer in pregnant women: laparoscopic evaluation before delaying treatment”. Eur. J. Gynaecol. Oncol., 2005, 26, 649.
[19] Charkviani L., Charkviani T., Natenadze N., Tsitsishvili Z.: “Cervical carcinoma and pregnancy”. Clin. Exp. Obstet. Gynecol., 2003, 30, 19.
[20] Benhaim Y., Haie-Meder C., Lhomme C., Pautier P., Duvillard P., Castaigne D., Morice P.: “Chemoradiation therapy in pregnant patients treated for advanced-stage cervical carcinoma during the first trimester of pregnancy: report of two cases”. Int. J. Gynecol. Cancer, 2007, 17, 270.
[21] Sorosky J.I., Squatrito R., Ndubisi B.U., Anderson B., Podczaski E.S., Mayr N. et al.: “Stage I squamous cell carcinoma in pregnancy: planned delay in therapy awaiting fetal maturity”. Gynecol. Oncol., 1995, 59, 207.
[22] Takushi M., Moromizato H., Sakumoto K., Kanazawa K.: “Management of invasive carcinoma of the uterine cervix associated with pregnancy: outcome of intentional delay in treatment”. Gynecol. Oncol., 2002, 87, 185.
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