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Original Research

Open Access

Interval debulking in epithelial ovarian carcinomas: the past, present and the future

M. Gultekin^1,*,
K. Diribas¹
E. Buru¹
P. Dursun²
K. Yuce³
A. Ayhan²

¹Department of Obstetrics and Gynecology, Cankiri Government Hospital, Cankiri, Turkey

²Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Baskent University School of Medicine, Maltepe, Ankara, Turkey

³Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Hacettepe University School of Medicine, Sihhiye, Ankara, Turkey

DOI: 10.12892/ejgo200803242 Vol.29,Issue 3,May 2008 pp.242-245

Published: 10 May 2008

*Corresponding Author(s): M. Gultekin E-mail: mrtgultekin@yahoo.com

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Abstract

Primary cytoreductive surgery followed by combination chemotherapy of paclitaxel and cisplatinum is the standard treatment for advanced staged epithelial ovarian cancers. Despite the maximal efforts to increase optimal cytoreductive success rates and related ultra-radical surgeries, five-year survival rates are still poor. Primary cytoreductive surgeries and their radicalities have been criticized since the early nineties. Interval debulking surgery (IDS) and neo-adjuvant chemotherapy (NAC) are the two suggested alternatives to the primary debulking approaches. In this article, the authors summarize and discuss the IDS approach with an associated literature review.

Keywords

Interval debulking surgery; Interval laparotomy; Epithelial ovarian carcinoma

Cite and Share

M. Gultekin,K. Diribas,E. Buru,P. Dursun,K. Yuce,A. Ayhan. Interval debulking in epithelial ovarian carcinomas: the past, present and the future. European Journal of Gynaecological Oncology. 2008. 29(3);242-245.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200803242

References

[1] Huober J., Meyer A., Wagner U., Wallwiener D.: “The role of neoadjuvant chemotherapy and interval laparotomy in advanced ovarian cancer”. J. Cancer Res. Clin. Oncol., 2002, 128, 153.

[2] Chan J.K., Manuel M., Osann K., Cheung M.K.: “Progress and trends in ovarian cancer survival over the last 15 years”. Abstract on Annual Meetings on Women’s Cancer. Society of Gynecologic Oncology, 2005.

[3] Skirnisdottir I., Sorbe B.: “Prognostic factors for surgical outcome and survival in 447 women treated for advanced (FIGO-Stages IIIIV) epithelial ovarian carcinoma”. Int. J. Oncol., 2007, 30, 727.

[4] Eisenhauer E.L., Abu-Rustum N.R., Sonoda Y., Levine D.A., Poynor E.A., Aghajanian C. et al.: “The addition of extensive upper abdominal surgery to achieve optimal cytoreduction improves survival in patients with Stages IIIC-IV epithelial ovarian cancer”. Gynecol. Oncol., 2006, 103, 1083.

[5] Aletti G.D., Dowdy S.C., Gostout B.S., Jones M.B., Stanhope C.R., Wilson T.O., Podratz K.C., Cliby W.A.: “Aggressive surgical effort and improved survival in advanced-stage ovarian cancer”. Obstet. Gynecol., 2006, 107, 77.

[6] Bristow R.E., Tomacruz R.S., Armstrong D.K., Trimble E.L., Montz F.J.: “Survival effect of maximal cytoreductive surgery for advanced ovarian carcinoma during the platinum era: a metaanalysis”. J. Clin. Oncol., 2002, 20, 1248.

[7] Hunter R.W., Alexander N.D., Soutter W.P.: “Meta-analysis of surgery in advanced ovarian carcinoma: is maximum cytoreductive surgery an independent determinant of prognosis?”. Am. J. Obstet. Gynecol., 1992, 166, 504.

[8] Covens A.L.: “A critique of surgical cytoreduction in advanced ovarian cancer”. Gynecol. Oncol., 2000, 78, 269.

[9] Morice P., Brehier-Ollive D., Rey A., Atallah D., Lhomme C., Pautier P. et al.: “Results of interval debulking surgery in advanced stage ovarian cancer: an exposed-non-exposed study”. Ann. Oncol., 2003, 14, 74.

[10] Vergote I., de Wever I., Tjalma W., Van Gramberen M., Decloedt J., Van Dam P.: “Interval debulking surgery: an alternative for primary surgical debulking?”. Semin. Surg. Oncol., 2000, 19, 49.

[11] Gallo A., Frigerio L.: “Neoadjuvant chemotherapy and surgical considerations in ovarian cancer”. Curr. Opin. Obstet. Gynecol., 2003, 15, 25.

[12] Pecorelli S., Odicino F., Favalli G.: “Interval debulking surgery in advanced epithelial ovarian cancer”. Best. Pract. Res. Clin. Obstet. Gynaecol., 2002, 16, 573.

[13] Schwartz P.E.: “Neoadjuvant chemotherapy for the management of ovarian cancer”. Best. Pract. Res. Clin. Obstet. Gynaecol., 2002, 16, 585.

[14] Redman C.W., Warwick J., Luesley D.M., Varma R., Lawton F.G., Blackledge G.R.: “Intervention debulking surgery in advanced epithelial ovarian cancer”. Br. J. Obstet. Gynaecol., 1994, 101, 142.

[15] van der Burg M.E., van Lent M., Buyse M., Kobierska A., Colombo N., Favalli G. et al.: “The effect of debulking surgery after induction chemotherapy on the prognosis in advanced epithelial ovarian cancer. Gynecological Cancer Cooperative Group of the European Organization for Research and Treatment of Cancer”. N. Engl. J. Med., 1995, 332, 629.

[16] Kehoe S., Shafi M., Luesley D.: “Interval cytoreduction in ovarian cancer (letter)”. N. Engl. J. Med., 1995, 333, 254.

[17] Neijt J.P.: “Interval cytoreduction in ovarian cancer (letter)”. N. Engl. J. Med., 1995, 333, 254.

[18] Cannistra S.A.: “Interval cytoreduction in ovarian cancer (letter)”. N. Engl. J. Med., 1995, 333, 255.

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