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Original Research

Open Access

Vaginal paraganglioma presenting as a gynecologic mass: case report

  • J.G. Shen1
  • Y.X. Chen2,*,
  • D.Y. Xu1
  • Y.F. Feng1
  • Z.H. Tong1

1Department of Endocrinology, The First Affiliated Hospital, School of Medicine, Zhejiang University, P.R. China

2Department of Gynecologic Oncology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, P.R. China

DOI: 10.12892/ejgo200802184 Vol.29,Issue 2,March 2008 pp.184-185

Published: 10 March 2008

*Corresponding Author(s): Y.X. Chen E-mail: chenyax@zju.edu.cn

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Abstract

Paragangliomas in the vagina are extremely rare. Unwitting surgical excision of a functional paraganglioma may precipitate life-threatening complications. We present a case of a 38-year-old woman with a vaginal mass 3.0 cm in diameter who experienced a hypertensive crisis during an unwitting attempted surgical excision of the vaginal mass. The diagnosis of a vaginal functional paraganglioma was then made based on to her 16-year history of paroxysmal headaches, chest distress, palpitation and elevated levels of urinary vannillylmandelic acid (VMA). Consequently, after thorough presurgical preparation, the patient again underwent excision of the vaginal mass uneventfully. She has been followed-up for three years since surgery without any evidence of recurrence. The clinical features and perioperative management of functional vaginal paraganglioma are described.

Keywords

Paraganglioma; Vagina; Perioperative management; Hypertension crisis

Cite and Share

J.G. Shen,Y.X. Chen,D.Y. Xu,Y.F. Feng,Z.H. Tong. Vaginal paraganglioma presenting as a gynecologic mass: case report. European Journal of Gynaecological Oncology. 2008. 29(2);184-185.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200802184

References

[1] Hassan A., Bennet A., Bhalla S., Ylagan, L.R., Mutch D., Dehner L.P.: “Paraganglioma of the vagina: report of a case, including immunohistochemical and ultrastructural findings”. Int. J. Gynecol. Pathol., 2003, 22, 404.

[2] Pezeshkpour G.: “Solitary paraganglioma of the vagina: Report of a case”. Am. J. Obstet. Gynecol., 1981, 138, 219.

[3] Parkes S.E., Raafat F., Morland B.J.: “Paraganglioma of the vagina: The first report of a rare tumor in a child”. Pediatr. Hematol. Oncol., 1998, 15, 545.

[4] Plate W.P.: “Phaeochromo-blastoma of the vagina”. Gynecologia, 1955, 139, 35.

[5] Erickson D., Kudva Y.C., Ebersold M.J., Thompson G.B., Grant C.S., van Heerden J.A. et al.: “Benign paraganglioma: clinical presentation and treatment outcomes in 236 patients”. J. Clin. Endocrinol. Metab., 2001, 86, 5210.

[6] Lenders J.W., Eisenhofer G., Mannelli M., Pacak K.: “Phaeochromocytoma”. Lancet, 2005, 366, 665.

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