Article Data

  • Views 413
  • Dowloads 126

Original Research

Open Access

Primary ovarian choriocarcinoma mimicking ectopic pregnancy managed with laparoscopy - case report

  • Y.X. Chen1
  • J. Xu2
  • W.G. Lv1
  • X. Xie1,*,

1Department of Gynecologic Oncology, P.R. China

2Department of Reproductive Medicine, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, P.R. China

DOI: 10.12892/ejgo200802174 Vol.29,Issue 2,March 2008 pp.174-176

Published: 10 March 2008

*Corresponding Author(s): X. Xie E-mail: /

Abstract

Nongestational ovarian choriocarcinomas are extremely rare and pose diagnostic challenges in reproductive-aged patients because of elevated human chorionic gonadotrophin (hCG). A 23-year-old nulliparous Chinese woman with nongestational ovarian choriocarcinoma escaped diagnostic testing and was initially treated for an ectopic pregnancy. Three months after her first visit, a diagnostic laparoscopy demonstrated a nongestational ovarian choriocarcinoma. Comprehensive surgical staging was performed by laparoscopy. The tumor was confined to the left ovary. The patient was categorized as FIGO Stage IA. She was given four courses of combined chemotherapy after laparoscopic surgery and has been disease-free for 36 months.

Keywords

Nongestational ovarian choriocarcinoma; Human chorionic gonadotrophin; Laparoscopy; Chemotherapy

Cite and Share

Y.X. Chen,J. Xu,W.G. Lv,X. Xie. Primary ovarian choriocarcinoma mimicking ectopic pregnancy managed with laparoscopy - case report. European Journal of Gynaecological Oncology. 2008. 29(2);174-176.

References

[1] Lai C.H., Chang T.C., Hsueh S., Wu T.I., Chou H.H., Wang P.N.: “Outcome and prognostic factors in ovarian germ cell malignancies”. Gynecol. Oncol., 2005, 96, 784.

[2] Oliva E., Andrada E., Pezzica E., Prat J.: “Ovarian carcinomas with choriocarcinomatous differentiation”. Cancer, 1993, 72, 2441.

[3] Sjovall K., Nilsson B., Einhorn N.: “Different types of rupture of the tumor capsule and the impact on survival in early ovarian carcinoma”. Int. J. Gynecol. Cancer, 1994, 4, 333.

[4] Sainz de la Cuesta R., Goff B.A., Fuller A.F. Jr, Nikrui N., Eichhorn J.H., Rice L.W.: “Prognostic importance of intraoperative rupture of malignant ovarian epithelial neoplasms”. Obetet. Gynecol., 1994, 84, 1.

[5] Yoon G.H., Stein J.P., Skinner D.G.: “Retroperitoneal lymph node dissection in the treatment of low-stage nonseminomatous germ cell tumors of the testicle: an update”. Urol. Oncol., 2005, 23, 168.

[6] Allaf M.E., Bhayani S.B., Link R.E., Schaeffer E.M., Varkarakis J.M., Shadpour P. et al.: “Laparoscopic retroperitoneal lymph node dissection: duplication of open technique”. Urology, 2005, 65, 575.

[7] Spirtos N.M., Eisekop S.M., Boike G., Schlaerth J.B.,Cappellari J.O.: “Laparoscopic staging in patients with incompletely staged cancers of the uterus, ovary, fallopian tube, and primary peritoneum: a Gynecologic Oncology Group (GOG) study”. Am. J. Obstet. Gynecol., 2005, 193, 1645.

[8] Tsujioka H., Hamada H., Miyakawa T., Hachisuga T., Kawarabayashi T.: “A pure nongestational choriocarcinoma of the ovary diagnosed with DNA polymorphism analysis”. Gynecol. Oncol., 2003, 89, 540.

[9] Williams S.D., Blessing J.A., Liao S.Y., Ball H., Hanjani P.: “Adjuvant therapy of ovarian germ cell tumors with cisplatin, etoposide and bleomycin: an adjuvant trial of the Gynecologic Group”. J. Clin. Oncol., 1994, 12, 701.

[10] Gatta G., Ciccolallo L., Kunkler I., Capocaccia R., Berrino F., Coleman M.P., et al.: “Survival from rare cancer in adults: a population- based study”. Lancet Oncol., 2006, 7, 132.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top