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Recurrence of granulosa cell tumor 25 years after initial diagnosis. Report of a case and review of the literature

  • D. Hasiakos1
  • K. Papakonstantinou1,*,
  • E. Karvouni2
  • S. Fotiou1

12nd Department of Obstetrics and Gynecology, Greece

2Department of Pathology, University of Athens, School of Medicine, Aretaieion Hospital, Athens, Greece

DOI: 10.12892/ejgo20080186 Vol.29,Issue 1,January 2008 pp.86-88

Published: 10 January 2008

*Corresponding Author(s): K. Papakonstantinou E-mail: kpapakon@yahoo.gr

Abstract

Granulosa cell tumors (GCTs) are rare functional sex cord-stromal ovarian tumors constituting approximately 2-3% of all ovarian malignancies. They are characterized by low malignant potential, local spread, late recurrence and high survival rates. We report a case of recurrent ovarian GCT in a 60-year-old woman 25 years after the initial diagnosis. The patient underwent surgical resection of the pelvic masses and refused to receive any adjuvant treatment, considering the late recurrence and high survival rates of this tumor. This case illustrates an example of a very late recurrence and emphasizes the importance of the extended follow-up required for these patients.

Keywords

Adult granulosa cell tumor; Recurrence

Cite and Share

D. Hasiakos,K. Papakonstantinou,E. Karvouni,S. Fotiou. Recurrence of granulosa cell tumor 25 years after initial diagnosis. Report of a case and review of the literature. European Journal of Gynaecological Oncology. 2008. 29(1);86-88.

References

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[8] Wolf J.K., Mullen J., Eifel P.J., Burke T.W., Levenback C., Gershenson D.M.: “Radiation treatment of advanced or recurrent granulosa cell tumor of the ovary”. Gynecol. Oncol., 1999, 73, 35.

[9] Uygun K., Aydiner A., Saip P., Kocak Z., Basaran M., Dincer M., Topuz E.: “Clinical parameters and treatment results in recurrent granulosa cell tumor of the ovary”. Gynecol. Oncol., 2003, 88, 400.

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[12] Hasiakos D., Papakonstantinou K., Goula K., Karvouni E., Fotiou S.: “Juvenile granulosa cell tumor associated with pregnancy. Report of a case and review of the literature”. Gynecol. Oncol., 2006, 100, 426.

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