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Paget's disease of the vulva - a review of our experience

  • S. Petkovie1,*,
  • K. Jeremie1
  • S. Vidakovic1
  • J. Jeremie1
  • G. Lazovie1

1Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia and Montenegro

DOI: 10.12892/ejgo200606611 Vol.27,Issue 6,November 2006 pp.611-612

Published: 10 November 2006

*Corresponding Author(s): S. Petkovie E-mail:

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Abstract

Objective: The aim of our study was to review our experience with Paget's disease of the vulvar relative to initial examination, treatment and oncological outcome.

Methods: Ten women with extramammary Paget's diseases of the vulva were treated during the 10-year period. The charts of these patients were reviewed and data were collected regarding patient demographics, symptoms, previous Paget's disease, surgical treatments and time to recurrence.

Results: Eight women (80%) were treated with wide local excision or partial vulvectomy, and two patients (20%) required radical resection for invasive adenocarcinoma. The group of women who had invasive diseases also underwent inquinofemoral lymphadenectomy and no lymphatic metastases were noted. Three women (30%) experienced recurrence. The mean time to relapse was 30 months (range 3-88 months).

Conclusion: Recurrence is very common and long-term monitoring is recommended with careful examination of any abnormal vulvar lesion.

Keywords

Paget's disease; Vulva

Cite and Share

S. Petkovie,K. Jeremie,S. Vidakovic,J. Jeremie,G. Lazovie. Paget's disease of the vulva - a review of our experience. European Journal of Gynaecological Oncology. 2006. 27(6);611-612.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200606611

References

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[2] Taylor P.T., Stenwig J.T., Klausen H.: "Paget's disease of the vulva". Gynaecol. Oncol., 1975, 3, 46.

[3] Tskada Y., Ramon G., Piver M.S.: "Paget's disease of the vulva: a clinicopathological study of eight cases". Obstet. Gynaecol., 1975, 45, 73.

[4] Curtin J.P., Rubin S.C., Jones W.B.: "Paget's disease of the vulva". Gynaecol. Oneal., 1990, 39, 374.

[5] Friedrich E., Wilkinson E.: "Paget's disease of the vulva and carcinoma of the breast". Obstet. Gynaecol., 1975, 46, 130.

[6] Bergen S., DiSaia P.J.: "Conservative management of extramammary disease Paget's of the vulva". Gynaecol. Oneal., 1989, 33, 156.

[7] Feuer G.A.: "Vulvar Paget's disease: the need to exclude an invasive lesion". Gynaecol. Oncol., 1990, 39, 377.

[8] Hoffman M.S., Cavanagh D.: "Malignancies of the vulva". In: Rock J.A. (ed.). Te Linde's Operative Gynecology, 8 th edition, Philadelphia, Lippincott-Raven, 1997, 1370.

[9] Stephen M.D., Richard M.D.: "Paget's disease of the vulva". Am J. Obstet. Gynecol., 2002, 187, 284.

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