Article Menu

Export Article

More by Authors Links

Article Data

  • Views 367
  • Dowloads 105

Case Reports

Open Access

Squamous cell carcinoma arising in a mature cystic teratoma of the ovary with synchronous invasive lobular breast cancer: case report

  • G.M. Filippakis1
  • E.E. Lagoudianakis1
  • M. Genetzakis1
  • P. Antonakis1
  • A. Papadima1
  • A. Boussiotou1
  • V. Katergiannakis1
  • A. Manouras1,*,

1First Department of Propaedeutic Surgery, Hippocrateion Hospital, Athens Medical School, Athens, Greece

DOI: 10.12892/ejgo200605537 Vol.27,Issue 5,September 2006 pp.537-540

Published: 10 September 2006

*Corresponding Author(s): A. Manouras E-mail:

PDF (2.1 MB)

Abstract

Malignant transformation of a mature ovarian cystic teratoma is the most serious complication of this relatively common neoplastic lesion. While any constituent tissue of the teratoma can undergo malignant transformation, squamous cell carcinoma represents approximately 80% of those malignancies. Furthermore, the synchronous occurrence of a second malignancy in that setting is extremely rare. Preoperative diagnosis of malignant transformation within a mature cystic teratoma is extremely difficult and poses a great challenge to current clinical surgical practice. The particularly aggressive behavior of this rare tumor, also poses significant surgical managing dilemmas. We present a case report of a premenopausal woman with an invasive squamous cell carcinoma arising in a mature cystic teratoma and a synchronous invasive lobular carcinoma of the breast.

Keywords

Mature cystic teratoma; Squamous cancer; Synchronous neoplasia; Multiple gynecological cancers

Cite and Share

G.M. Filippakis,E.E. Lagoudianakis,M. Genetzakis,P. Antonakis,A. Papadima,A. Boussiotou,V. Katergiannakis,A. Manouras. Squamous cell carcinoma arising in a mature cystic teratoma of the ovary with synchronous invasive lobular breast cancer: case report. European Journal of Gynaecological Oncology. 2006. 27(5);537-540.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200605537

References

[1] Tseng C.J., Chou H.H., Huang K.G.. Chang T.C., Liang C.C., Lai C.H. et al.: "Squamous cell carcinoma arising in mature cystic teraroma of the ovary". Gynecol. Oncol., 1996. 63, 364.

[2] Peterson W.F.: "Malignant degeneration of benign cystic teratomas of the ovary; a collective review of the literature". Ohstet. Gynecol. Surv., 1957, 12, 793.

[3] Kelley R.R., Scully R.E.: "Cancer developing in dermoid cysts of the ovary. A report of 8 cases, including a carcinoid and a leiomyosarcoma". Cancer, 1961, 14. 989.

[4] Stamp G.W.H., McConnell E.M.: ·'Malignancy arising in cystic ovarian teratomas. A report of 24 cases". Br. J. Ohstet. Gynaecol., 1983, 90, 671.

[5] Hirakawa T., T suneyoshi M., Enjoji M.: "Squamous cell carcinoma arising in ovarian mature cystic teratoma: Clinicopathological and topographic analysis". Am. J. Surg. Pathol., 1989, 13,397.

[6] Chen R.J., Huang P.T., Lin M.C., Huang S.C., Chow S.N., Hsieh C. Y.: "Advanced stage squamous cell carcinoma arising from mature cystic teratoma of the ovary". Acta Ohstet. Gynecol Scand., 2001, 80, 84.

[7] Eisner R.F., Nieberg R.K., Berek J.S.: "Synchronous pnmary neoplasms of the female reproductive tract". Gynecol. Oneal.. 1989, 33, 335.

[8] Outwater E.K., Siegehnan E.S.: "Ovarian teratomas: Tumor types and imaging characteristics·•. RadioGraphics, 2001, 21, 475.

[9] Mori Y., Nishii H., Takabe K.. Shinozaki H., Matsumoto N., Suzuki K. et al.: "Preoperative diagnosis of malignant transformation arising from mature cystic teratoma of the ovary". Gynecol Oncol., 2003, 90, 338.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top