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Refractory metastatic choriocarcinoma treated surgically with polychemotherapy - case report
1Institute of Obstetrics and Gynecology, Clinical Center of Serbia, Belgrade, Serbia and Montenegro
2Institute for Aplication of Nuclear Energy-INEP, Zemun, Serbia and Montenegro
*Corresponding Author(s): M. Petronijevic E-mail:
The authors present the course of treatment of refractory metastatic choriocarcinoma in a 49-year-old woman was treated surgically by hysterectomy and resection of suprarenal gland metastases. During the treatment the patient received 15 courses of polychemotherapy with different protocols. After five years of treatment and seven years of follow-up there is no evidence of recurency of the disease.
Choriocarcinoma; Metastasis; Suprarenal gland; Polychemotherapy
M. Petronijevic,S. Vrzic-Petronijevic,V. Boskovic,D. Bratic,Lj. Vicovac. Refractory metastatic choriocarcinoma treated surgically with polychemotherapy - case report. European Journal of Gynaecological Oncology. 2006. 27(5);523-525.
[1] Berkowitz R.S., Goldstein D.P.: "Recent advances in gestational trophoblastic disease". Curr. Opin. Obstet. Gynecol., 1998, 10, 61.
[2] Ilancheran A.: "Optimal treatment in gestational trophoblastic disease". Ann. Acad. Med. Singapore, 1998, 27, 698.
[3] Lukovic-Jovanovic R.: "Dijagnostika i terapija trofoblastnih tumora. Doktorska disertacija". Medicinski fakultet u Beogradu, 1980.
[4] Newlands E.S., Bower M., Holden L., Short D., Seek! M.J.. Rustm G.J. et al.: "Management of resistant gestational trophoblastic tumors". J. Reprod. Med., 1998, 43, 111.
[5] Piamsomboon S., Kudelka A.P., Termrungruanglert W., Van Bes1en K., Edwards C.L., Lifshitz S. et al.: "Remission of refractory gestational trophoblastic disease in the brain with ifosfamide, carboplatin, and etoposide (ICE): first report and review of literature". Eur. J. Gynaecol. Oneal., 1997, 18,453.
[6] Preidler K.W., Luschin G., Tamussino K., Szolar D.M., Stiskal M., Ebner F.: "Magnetic resonance imaging in patients with gestational trophoblastic disease". Invest. Radiol., 1996, 31,492.
[7] van Besien K., Verschraegen C., Mehra R., Giralt S., Kudelka A.P., Edwards C.L. et al.: "Complete remission of refractory gestational trophoblastic disease with brain metastases treated with multicycle ifosfamide, carboplatin, and etoposide (ICE) and stem cell rescue" Gynecol. Oneal., 1997, 65, 366.
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