Article Data

  • Views 367
  • Dowloads 122

Case Reports

Open Access

Synchronous primary cancers of the endometrium and ovary: a case report

  • K. Giizin1
  • C. Tekcan1
  • M.M. Naki1,*,
  • S. Kayatas1
  • E. Zemheri2
  • F. Kanadikink1
  • S. Berkman3

1Department of Obstetrics and Gynecology, Turkey

2Department of Pathology, Goztepe Research and Education Hospital, Turkey

3Department of Obstetrics and Gynecology, University of Istanbul, Faculty of Medicine, Istanbul, Turkey

DOI: 10.12892/ejgo200604425 Vol.27,Issue 4,July 2006 pp.425-428

Published: 10 July 2006

*Corresponding Author(s): M.M. Naki E-mail:

Abstract

Synchronous primary cancers of the endometrium and ovary are found in 5% of women with endometrial cancer and 10% of women with ovarian cancer. In the present case, a multigravid 46-year-old woman complained of lower abdominal pain and abdominal distension. She did not define abnormal uterine bleeding. Screening ultrasound revealed a papillary containing structure, irregular, cystic 16 x 15 x 10 cm right ovarian mass. Preoperative endometrial biopsy revealed endometrioid adenocarcinoma. Ascites sampling, radical hysterectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymphadenectomy, omentectomy, appendectomy and cytologic sampling of the undersurface of the diaphragm were carried out. Intraoperative and histological examinations showed Stage IIIC papillary serous carcinoma and stage IC endometrioid adenocarcinoma. Synchronous genital tract neoplasms constitute a more common clinical problem than would generally be expected.

Keywords

Synchronous; Primary cancer; Endometrium; Ovary

Cite and Share

K. Giizin,C. Tekcan,M.M. Naki,S. Kayatas,E. Zemheri,F. Kanadikink,S. Berkman. Synchronous primary cancers of the endometrium and ovary: a case report. European Journal of Gynaecological Oncology. 2006. 27(4);425-428.

References

[1] Zaino R., Whitney C. et al.: "Simultaneously detected endometrial and ovarian carcinomas- A prospective clinicopathologic study of 74 cases : A gynecologic oncology group study". Gynecol. Oneal., 2001, 83, 355.

[2] Ulbright T., Roth L.: "Metastatic and independent cancers of the endometrium and ovary: a clinicopathologic study of 34 cases". Hum. Pathol., 1985, 16, 28.

[3] Eisner R.F., Nieberg R.K., Berek J.S.: "Synchronous primary neoplasms of the female reproductive tract". Gynecol. Oneal., 1989, 33, 335.

[4] Haberin R., Zehavi S., Hadas E., Habler L., Bukovsky I., Schneider D.: "Simultaneous carcinoma of the endometrium and ovary vs. endometrial carcinoma with ovarian metastases: A clinical and immunohistochemical determination". Int. J. Gynecol. Cancer, 2003, 13, 32.

[5] Soliman P.T., Slomovitz B.M. et al.: "Sychronous pnmary cancers of the endometrium and ovary: a single institution review of 84 cases". Gynecol. Oncol., 2004, 94, 456.

[6] P earl M.L., Frank T.S., Roberts J.A.: "Synchronous dual primary ovarian and endometrial carcinomas". Int. J. Gynecol. Obstet., 1993, 43, 305.

[7] Woodruff J.D., Solomon D., Sullivant H.: "Multifocal disease in the upper genital canal". Obstet. Gynecol., 1985, 65, 695.

[8] Castro J.M., Connell P.P., Waggoner S., Rotmensch J., Mundt A.J.: "Synchronous ovarian and endometrial malignancies". Am. J. Clin. Oncol., 2000, 23, 521.

[9] Efiel P., Hendrickson M., Ross J., Ballon S., Mantinez A., Kempson R.: "Simultaneous presentation of carcinoma involving the ovary and endometrium". Cancer, 1982, 50, 163.

[10] Prat J., Matias-Guiu X., Bareto J.: "Simultaneous carcmoma involving the endometrium and the ovary. A clinicopathologic, immunohistochemical, and DNA flow cytometric study of 18 cases". Cancer, 1991, 68, 2455.

[11] Lukanova A., Toniolo P. et al.: "Body mass index in relation to ovarian cancer: a multi-centre nested case-control study". Int. J. Cancer, 2002, 99, 603.

[12] Engeland A., Tretli S., Bjorge T.: "Height, body mass index.and ovarian cancer: a follow-up of I.I million Norwegian women". J. Natl. Cancer Inst., 2003, 95, 1244.

[13] P iura B., Glezarman M.: "Synchronous carcinomas of endometrium and ovary". Gynecol. Oneal., 1989, 33, 261.

[14] Zino R.J., Under E.R., W hitney C.: "Synchronous carcinomas of uterin corpus and ovary". Gynecol. Oneal., 1984, 19, 329.

[15] Ayhan A., Yalcin O.T., Tuncer Z.S., Gurgan T., Kucukali T.: "Synchronous malignancies of the female genital tract". Eur. J. Obstet. Gynecol. Reprod. Biol., 1992, 45, 63.

[16] Brown G.J.E., St John D.J.B. et al.: "Cancer risk m young women at risk of hereditary nonpolyposis colorectal cancer: implications for gynecologic surveillance". Gynecol. Oneal., 2001, 80, 346.

[17] Lynch H.T., Watson P.: "Ovarian cancer in hereditary nonpolyposis colorectal cancer (HNPCC): report of the International Colloborative Group on HNPCC (ICG-HNPCC)". Pro c. Am. Clin. Oneal., 2002, 19, 604a.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top