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Case Reports

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Synchronous primary cancers of the endometrium and ovary: a case report

  • K. Giizin1
  • C. Tekcan1
  • M.M. Naki1,*,
  • S. Kayatas1
  • E. Zemheri2
  • F. Kanadikink1
  • S. Berkman3

1Department of Obstetrics and Gynecology, Turkey

2Department of Pathology, Goztepe Research and Education Hospital, Turkey

3Department of Obstetrics and Gynecology, University of Istanbul, Faculty of Medicine, Istanbul, Turkey

DOI: 10.12892/ejgo200604425 Vol.27,Issue 4,July 2006 pp.425-428

Published: 10 July 2006

*Corresponding Author(s): M.M. Naki E-mail:

Abstract

Synchronous primary cancers of the endometrium and ovary are found in 5% of women with endometrial cancer and 10% of women with ovarian cancer. In the present case, a multigravid 46-year-old woman complained of lower abdominal pain and abdominal distension. She did not define abnormal uterine bleeding. Screening ultrasound revealed a papillary containing structure, irregular, cystic 16 x 15 x 10 cm right ovarian mass. Preoperative endometrial biopsy revealed endometrioid adenocarcinoma. Ascites sampling, radical hysterectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymphadenectomy, omentectomy, appendectomy and cytologic sampling of the undersurface of the diaphragm were carried out. Intraoperative and histological examinations showed Stage IIIC papillary serous carcinoma and stage IC endometrioid adenocarcinoma. Synchronous genital tract neoplasms constitute a more common clinical problem than would generally be expected.

Keywords

Synchronous; Primary cancer; Endometrium; Ovary

Cite and Share

K. Giizin,C. Tekcan,M.M. Naki,S. Kayatas,E. Zemheri,F. Kanadikink,S. Berkman. Synchronous primary cancers of the endometrium and ovary: a case report. European Journal of Gynaecological Oncology. 2006. 27(4);425-428.

References

[1] Zaino R., Whitney C. et al.: "Simultaneously detected endometrial and ovarian carcinomas- A prospective clinicopathologic study of 74 cases : A gynecologic oncology group study". Gynecol. Oneal., 2001, 83, 355.

[2] Ulbright T., Roth L.: "Metastatic and independent cancers of the endometrium and ovary: a clinicopathologic study of 34 cases". Hum. Pathol., 1985, 16, 28.

[3] Eisner R.F., Nieberg R.K., Berek J.S.: "Synchronous primary neoplasms of the female reproductive tract". Gynecol. Oneal., 1989, 33, 335.

[4] Haberin R., Zehavi S., Hadas E., Habler L., Bukovsky I., Schneider D.: "Simultaneous carcinoma of the endometrium and ovary vs. endometrial carcinoma with ovarian metastases: A clinical and immunohistochemical determination". Int. J. Gynecol. Cancer, 2003, 13, 32.

[5] Soliman P.T., Slomovitz B.M. et al.: "Sychronous pnmary cancers of the endometrium and ovary: a single institution review of 84 cases". Gynecol. Oncol., 2004, 94, 456.

[6] P earl M.L., Frank T.S., Roberts J.A.: "Synchronous dual primary ovarian and endometrial carcinomas". Int. J. Gynecol. Obstet., 1993, 43, 305.

[7] Woodruff J.D., Solomon D., Sullivant H.: "Multifocal disease in the upper genital canal". Obstet. Gynecol., 1985, 65, 695.

[8] Castro J.M., Connell P.P., Waggoner S., Rotmensch J., Mundt A.J.: "Synchronous ovarian and endometrial malignancies". Am. J. Clin. Oncol., 2000, 23, 521.

[9] Efiel P., Hendrickson M., Ross J., Ballon S., Mantinez A., Kempson R.: "Simultaneous presentation of carcinoma involving the ovary and endometrium". Cancer, 1982, 50, 163.

[10] Prat J., Matias-Guiu X., Bareto J.: "Simultaneous carcmoma involving the endometrium and the ovary. A clinicopathologic, immunohistochemical, and DNA flow cytometric study of 18 cases". Cancer, 1991, 68, 2455.

[11] Lukanova A., Toniolo P. et al.: "Body mass index in relation to ovarian cancer: a multi-centre nested case-control study". Int. J. Cancer, 2002, 99, 603.

[12] Engeland A., Tretli S., Bjorge T.: "Height, body mass index.and ovarian cancer: a follow-up of I.I million Norwegian women". J. Natl. Cancer Inst., 2003, 95, 1244.

[13] P iura B., Glezarman M.: "Synchronous carcinomas of endometrium and ovary". Gynecol. Oneal., 1989, 33, 261.

[14] Zino R.J., Under E.R., W hitney C.: "Synchronous carcinomas of uterin corpus and ovary". Gynecol. Oneal., 1984, 19, 329.

[15] Ayhan A., Yalcin O.T., Tuncer Z.S., Gurgan T., Kucukali T.: "Synchronous malignancies of the female genital tract". Eur. J. Obstet. Gynecol. Reprod. Biol., 1992, 45, 63.

[16] Brown G.J.E., St John D.J.B. et al.: "Cancer risk m young women at risk of hereditary nonpolyposis colorectal cancer: implications for gynecologic surveillance". Gynecol. Oneal., 2001, 80, 346.

[17] Lynch H.T., Watson P.: "Ovarian cancer in hereditary nonpolyposis colorectal cancer (HNPCC): report of the International Colloborative Group on HNPCC (ICG-HNPCC)". Pro c. Am. Clin. Oneal., 2002, 19, 604a.

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