Article Data

  • Views 1490
  • Dowloads 131

Original Research

Open Access

Amerindian women of the Brazilian Amazon and STD

  • E.B. Brito1,*,
  • I.D.C Silva2
  • J.N. Stavale3
  • E. Taromaru4
  • R.C. Menezes5
  • S.J. Martins6

1Pathology Department, UNIFESP, Center for Tropical Medicine, UFPA

2Gynecology Department, UNIFESP

3Pathology Department, UNIFESP

4Digene of Brazil, Sao Paulo, SP

5Public Health USP, Health Subprogram-Program Parakana

6USP, Program Parakana, Brazail

DOI: 10.12892/ejgo200603279 Vol.27,Issue 3,May 2006 pp.279-281

Published: 10 May 2006

*Corresponding Author(s): E.B. Brito E-mail:

PDF (390.45 kB) View Full-text

Abstract

Papanicolaou tests, PCR for HPV, C. trachomatis, HSV-1/2 and N. gonorrhoea, and Hybrid Capture II were performed for high- and low-risk HPV groups during screening for cervical cancer in 49 women of the Parakana tribe. Cytological diagnoses of HPV were suggested in three samples: PCR showed 12 (22.4%) cases of DNA positive HPV, 16 (1), 18 (2), 58 (3), 39 (1), 61 (1), 33 (1), 35 (1), unknown (2), and HCII analyzed 48 samples: 19 positive (39.58%) for the high-risk group and four (18.33%) for the low-risk group. The prevalence of HPV was 42.85% (p = 0.001) by molecular biology methods. The largest viral load was 1588.11 pg/ml for HPV 39 in a 16-year-old. PCR was positive for C. trachomatis and negative for HSV-1/2 and N. gonorrhoea. Parakana women present a high risk for the development of cervical cancer.

Keywords

STD; High-risk HPV; Amerindian of the Amazonian; Prevention of cervical cancer

Cite and Share

E.b. Brito, I.d.c Silva, J.n. Stavale, E. Taromaru, R.c. Menezes, S.j. Martins. Amerindian women of the Brazilian Amazon and STD. European Journal of Gynaecological Oncology. 2006; 27(3): 279-281. doi: 10.12892/ejgo200603279

References

[1] Menezes R.C.: Report of the Sub-program of Health of the Parakana Program, 2003.

[2] Brito E.B., Menezes R.C., Martins S.J., Bastos M.G., Sousa A "Preliminary study on low trait genital infection cervical and epithelial dysplasia in women from the Parakana tribe of South America". Rev. Assoc. Med. Bras., 1996, 42, 11.

[3] Digene Brasil - Manual of Instructions. System of hybrid capture in microplaca of digene. Test for DNA-HPV, revised 02/2003.

[4] Benard H., Chan S., Brothers M., Ong C., Villa L.L., Delius H. et al.: "Identification an assessment of know and novel human papillomaviruses by polymerase chain reaction amplification, restriction fragment lengh polymorphisms, nucleotide sequence and phylogenetic algorithms". Journal Infect. Dis.,1994, 170, 1077.

[5] Jolly A.M., Orr P.H., Hammond G., Young T.K.: "Risk factors goes infection in women undergoing testing goes Chlamydia trachomatis and Neisseria gonorrhoeae in Manitoba, Canada". Sex. Transm. Dis., 1995, 22, 289.

[6] Kenney J.W.: "Ethnic differences in risk factors associated with genital human papillomavirus infections". J. Adv. Nurs., 1996, 23, 1221.

[7] Young T.K., Mcnicol P., Beauvaus J.: "Factors associated with human papillomavirus infection detected by polimerase chain reaction among urban Canadian aboriginal and non-aboriginal women [see comments]". Comment in: Sex Transm. Dis., 1998, 25, 55.

[8] Ong C.K., Bernard H.U., V仆la L.L.: "Identification of genomic sequences of three novel human papillomavirus sequences in cervical smears of amazonian indians [published erratum appears in J.I.D., 1996, 173, 516]". J. Infect. Dis., 1994, 170, 1086.

[9] Brito E.B., Villa L.L., Menezes R.C., Martins SJ.: "Human papillomavirus infection among women from a South American Indian Tribe". In: XIV FIGO, World Congress in Montreal, Canada, 1993.

[10] Boulanger J.C., Bauville A.N.D., Nasreddine T.H.E., Ghighi C., Sevestre H., Gondry J. et al.: "Epidemiology of HPV Infection in picardy and viral load", Abstract book. Eurogin, 2003, 105, SS6

[11] Brito E.B., Martins SJ., Menezes R.C.: "Human papillomaviruses in Amerindian women from Amazonian Brazilian". Epidemiol. Infect., 2002, 128, 485.

[12] Ho G.Y.F., Burk R.D., Klein S. et al.: "Persistent genital human papillomavirus infection the the risk factor goes persistent cervical dysplasia". J. Natl. Cancer Inst., 1995, 87, 1365.

[13] Buga G.A.: "Cancer awareness and risk factors among female University Student". East Afr. Med. J., 1998, 75, 411

[14] Franco E.L., Villa L., Rohan T., Ferenczy A., Petzl-Erler M., Matlashewski G.: "Design and methods of the Ludwig-McGill longitudinal study of the natural history of human papillomavirus infection and cervical neoplasia in Brazil". Ludwig-McGill Study Group. Rev. Panam Salud Publishes, 1999, 6, 223.

[15] Ferenczy T.H.E., Franco A.N.D., Arseneau J., Wright T.C., Richart R.M.: "Diagnostic performance of hybrid captures human papillomavirus deoxyribonucleic acid assay combined with liquid-based cytologic study". Am. J. Obstet Gynecol., 1996, 175 (3 pt 1), 651.

[16] Lorincz A.: "Portland study update". Eurogin 2003. Paris, April 13-16, 2003.

[17] Bisgaard K.: "A possible marker for diagnosis of cervical precancer- an alternative to HPV testing?". Final program and Abstracts book (SS5). Eurogin, Paris, France, 2003, 103.

[18] Sankaranarayana R.: "Emerging issues cervical in cancer screening: developing countries: He/she SAW". Abstracts book. Eurogin, Paris, 2003, 95.

[19] Jacinth C.,印ho Almeida G., Maldonado P.: "HPV - Genital Infection Feminine and Masculine". I" edition, Rio de Janeiro, Revinter, 1994.

[20] Koskela P., Anttila T., Bjorge T., Brunsvig T.H.E., Dillner J., Hakama M., Hakulinem T. et al.: "Chlamydia trachomatis infection the the risk factor goes invasive cervical cancer". Int. Cancer, 2000, 85, 35.

[21] Judlin P.: "Emerging issues of non viral STIS: complications and management of chronic diseases: addressing the issue". Abstracts Book, Eurogin, Paris, 2003, 82.

[22] Villa L.L.: "Human papillomaviruses and cervical cancer". Cancer Adv. Cancer Res., 1997, 71, 321.

[23] Vogin, Gay D.: "The study was funded by Merck & Company which manufactures the vaccine". 44th Interscience Conference on Antimicrobial Agents & Chemotherapy (ICAAC). Abstract 3741, presented in 2004.

Submission Turnaround Time

Top