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Treatment of choriocarcinoma metastases by surgery and polychemotherapy - case report

  • K. Jeremie1,*,
  • M. Gojnic1
  • V. Boskovie1
  • R. Argirovie1
  • V. Milenkovie1
  • J. Jeremie1

1Institute of Gynecology and Obstetrics, Clinical Center of Serbia, Belgrade, Serbia and Montenegro

DOI: 10.12892/ejgo200602162 Vol.27,Issue 2,March 2006 pp.162-164

Published: 10 March 2006

*Corresponding Author(s): K. Jeremie E-mail:

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Abstract

Choriocarcinoma is present in one out of every 40,000 pregnancies. There is a great risk for incidence of the disease in women who become pregnant after 45 years of age. The clinical picture may vary and is related to the destruction of tissue and bleeding. New chemo protocols containing etoposide, cisplatin, ifosfamide, together with a resection of the focus resistant to chemotherapy, lead in most cases to the complete recovery.

Keywords

Choriocarcinoma; Polychemotherapy

Cite and Share

K. Jeremie,M. Gojnic,V. Boskovie,R. Argirovie,V. Milenkovie,J. Jeremie. Treatment of choriocarcinoma metastases by surgery and polychemotherapy - case report. European Journal of Gynaecological Oncology. 2006. 27(2);162-164.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200602162

References

[1] Soper J.T., Lewis J.L., Hammond C.B.: "Gestational trophoblastic disease". In: Hoskins W.J., Perez C.A., Young R.C. (eds.). Principies and Practice of Gynecologic Oncology Philadelphia, Lippincott-Raven Pub!., 1996, 1039.

[2] Soper J.T., Evans A.C., Conway M.R. et al.: "Evaluation of prognostic factors and staging in gestational trophoblastic tumor" Obstet Gynecol., 1994, 84, 969.

[3] Berkowitz R.S., Goldstein D.P.: "Gestational trophoblastlc disease". In: Hoskin W.J.,P erez C.A.,Y oung R.C. (eds.). Princi ples and Practice of Gynecologic Oncology, Philadelphia, Lippincott Williams & W心ns,2000, 11, 17.

[4] Ng T.Y., Won L.C.: "Diagnosis and management of gestational trophoblastic neoplasia". Best Pract. Res. Clin. Obstet. Gynecol., 2003, 17, 893.

[5] T idy J.A., G仆lespie A.M., Bright N. et al.: "Gestational trophoblastic disease: a stady of mode of evacuation and subsequent need for treatment with chemotherapy". Gynecol. Oneal., 2000, 38,309.

[6] Wrigh J.D., Mutch D.G.: "Treatment of high risk gestational trophoblastic disease". Clin. Obstet. Gynecol., 2003, 17, 593.

[7] Bower M.: "EMA/CO for high risk gestational trophoblastic tumors: results from a cohort of 272 patients". J. Clin. Oneal., 1999, 15, 2636.

[8] Hammond C.B., Borchet L.G., Tyrey L. et al.: "Treatment of metastatic trophoblastic disease: good and poor prognosis". Am. J Obstet. Gynecol., 1973, 115, 451.

[9] Cohn D.E., Herzog H.T.: "Gestational trophoblastic disease: new standards for therapy". Curr. Opin. Oneal., 2000, 12, 492.

[10] Lurain J.R.: "Gestational trophoblastic tumors". Semin. Surg. Oncol.,1990, 6, 347.

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