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Case Reports

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Cutaneous metastasis of endometrial carcinoma with hemorrhagic nodules and papules

  • M. Baydar1
  • M. Dikilitas1
  • A. Sevinc2,*,
  • S. Senel1
  • F. Senel3
  • I. Aydogdu1

1Inonu University, School of Medicine, Department of Internal Medicine, Division of Hematology, Turgut Ozal Medical Center, Malatya, Turkey

2Gaziantep University, Department of Internal Medicine, Division of Medical Oncology, Sahinbey Medical Center, Gaziantep, Turkey

3Inonu University, School of Medicine, Department of Pathology, Turgut Ozal Medical Center, Malatya, Turkey

DOI: 10.12892/ejgo200504464 Vol.26,Issue 4,July 2005 pp.464-467

Published: 10 July 2005

*Corresponding Author(s): A. Sevinc E-mail:

Abstract

Background: Endometrium cancer is the fourth most frequent malignancy in women. However, skin metastasis from endometrium cancer is a very rare entity.

Case: A 58-year-old multiparous woman postmenopausal for ten years presented with multiple metastatic, nodular, hemorrhagic skin lesions located at the initial surgery and radiotherapy site 14 months after the original diagnosis was made. Combination chemotherapy was instituted, but the patient died after the second cycle of chemotherapy.

Conclusion: Although endometrial cancer is one of the most frequent malignancies in women, skin metastasis from endometrial cancer is very rare. In reported cases metastasis from endometrial cancer has been most commonly noted at the initial surgery and radiotherapy site. Therefore, the initial surgical and radiotherapy site must be examined carefully for skin metastasis.

Keywords

Endometrial carcinoma; Skin; Metastasis; Radiotherapy

Cite and Share

M. Baydar,M. Dikilitas,A. Sevinc,S. Senel,F. Senel,I. Aydogdu. Cutaneous metastasis of endometrial carcinoma with hemorrhagic nodules and papules. European Journal of Gynaecological Oncology. 2005. 26(4);464-467.

References

[1] Greenlee R.T., Murray T., Bolden S., Wingo P.A.: "Cancer statistics 1999". CA Cancer J. Clin., 2000, 50, 7.

[2] Espinos J.J., Garsia-Patos V., Guiu X.M., Delgado E.: "Early skin metastasis of endometrial adenocarcinoma: case report and review of the literature". Cutis, 1993, 52, 109.

[3] Kushner D.M., Lurain J.R., Fu TS., Fishman D.A.: "Endomemtrial adenocarcinoma metastatic to the scalp: case report and literature review". Gynecol. Oncol., 1997, 65, 530.

[4] Ozsaran A.A., Dikmen Y., Kazandi M., Terek M.C., Kazandi A.C., Erhan Y.: "Abdomjnal skin metastasis of endometrial adenocarcinoma: case report". Eur. J. Gynaecol. Oncol., 2002, 23, 264.

[5] Patel K.S., Watkins R.M.: "Recurrent endometrial adenocarcinoma presenting as an umblical metastasis (Sister Mary Joseph's Nodule)". Br. J. Clin. Pract., 1992, 46, 69.

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