Article Menu

Export Article

More by Authors Links

Article Data

  • Views 339
  • Dowloads 120

Case Reports

Open Access

Coexistence of Brenner tumor and struma ovarii: case report

  • K. Takeuchi1,*,
  • C. Ohbayashi2
  • S. Kitazawa3
  • N. Ohara1
  • T. Maruo1

1Department of Obstetrics and Gynecology, Japan

2Division of Surgical Pathology, Japan

3Division of Molecular Pathology, Kobe University Graduate School of Medicine, Kobe, Japan

DOI: 10.12892/ejgo200501109 Vol.26,Issue 1,January 2005 pp.109-110

Published: 10 January 2005

*Corresponding Author(s): K. Takeuchi E-mail:

PDF (1.53 MB)

Abstract

Background: There has been controversy regarding the histogenesis of Brenner tumors. It is generally accepted that Brenner tumors are derived directly from ovarian surface epithelium, which undergoes metaplasia to form the typical urothelial-like components, whereas some investigators assume that Brenner tumors arise from immature germ cells.

Case: We describe a well-documented case of the coexistence of struma ovarii regarded as a form of teratoma and Brenner tumor in the same ovary. Immunohistologically, not only columnar cells of thyroid follicles, but also transitional cells of Brenner nests were positive for thyroglobulin.

Conclusions: In the present case, Brenner tumors and thyroid elements coexisted and were positive for thyroglobulin. While there is strong evidence that pure Brenner tumors originate mostly from the ovarian surface, at least Brenner tumors associated with teratomatous elements may have a germ cell origin.

Keywords

Brenner tumor; Struma ovarii; Thyroglobulin

Cite and Share

K. Takeuchi,C. Ohbayashi,S. Kitazawa,N. Ohara,T. Maruo. Coexistence of Brenner tumor and struma ovarii: case report. European Journal of Gynaecological Oncology. 2005. 26(1);109-110.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200501109

References

[1] Russell P.: "Surface epithelial-stromal tumours of the ovary". In F ox H. (ed.). Haines & Taylor Obstetric and Gynecological Pathology, New York, Churchill Livingstone, 1995, 743.

[2] Nogales F.F.: "Germ cell tumours of the ovary". In: Fox H. (ed.) Haines & Taylor Obstetric and Gynecological Pathology. New York, Churchill Livingstone, 1995, 847.

[3] Moon S., Waxman M.: "Mixed ovarian tumor composed of Brenner and thyroid elements". Cancer, 1976, 38, 1997.

[4] Chiarelli S.M., Onnis G.L.: "Coexisting Brenner tumor and struma ovarii: case report". Eur. J. Gynaecol. Oneal., 1980, 1, 108.

[5] Carinelli S.G., Senzani F., Carinelli I., Cefis F.: "Struma ovarii and Brenner tumor". Tumori, 1981, 67, 581.

[6] Elemenoglou A., Zizi-Serbetzoglou A., Trihia H., Yasilakaki T., Bournia E.: "Mixed ovarian neoplasm composed of struma ovarii and Brenner tumour". Eur. J. Gynaecol. Oneal., 1994, 15, 138.

[7] Burg J., Kommoss F., Bittinger F., Moll R., Kirkpatrick C.J "Mature cystic teratoma of the ovary with struma and benign Brenner tumor: a case report with immunohistochemical charaterization". Int. J. Gynecol. Pathol., 2001, 21, 74.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top