Article Menu

Export Article

More by Authors Links

Article Data

  • Views 342
  • Dowloads 127

Original Research

Open Access

The use of erythropoietin in gynecologic cancer patients

  • G. Kourounis1
  • G. latrakis1
  • K. Chronopoulos1
  • K. Liatsos1
  • I. Ladopoulos1,*,

1Department of Obstetrics and Gynecology of Patras University, Greece

DOI: 10.12892/ejgo200406735 Vol.25,Issue 6,November 2004 pp.735-736

Published: 10 November 2004

*Corresponding Author(s): I. Ladopoulos E-mail:

PDF (144.45 kB)

Abstract

Purpose: To investigate the possible benefits of erythroproietin ingestion in patients with various gynecological cancers with proven severe iron deficiency anemia.

Method: Seven patients with gynecological cancer were included in the study. Nadir hematocrit values were found to be 20-24% before the initiation of recombinant human erythropoietin treatment. Initial therapy started at 50 units/kg/dose, three times weekly for a month. The dose was modified according to the rise of hemoglobin after a month's period. The dose was modified according to the rise of hemoglobin after a month's period. If the rise was greater than 2 g/dl the dose was changed to 25 units/kg two times weekly and if it was less than 2 g/dl it was changed to 25 units/kg three times weekly per month. Five patients were simultaneously given erythropoietin therapy and iron supplementation.

Results: We confirmed a rise in the hematocrit values which averaged 0.5-1.5% weekly till the upper limit. Reticulocyte and hematocrit values were higher in the erythropoietin plus iron group (five cases).

Conclusion: In this small series, erythropoietin appeared to be effective in treating severe iron deficiency in gynecologic cancer patients. Further investigation is needed to confirm these results.

Keywords

Gynecologic cancers; Severe anemia; Erythropoietm

Cite and Share

G. Kourounis,G. latrakis,K. Chronopoulos,K. Liatsos,I. Ladopoulos. The use of erythropoietin in gynecologic cancer patients. European Journal of Gynaecological Oncology. 2004. 25(6);735-736.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200406735

References

[1] Albertazzi A., Di Liberato L., Daniele F., Battiste! V., Colombi L.: "Efficacy and tolerability of recombinant human erythropoietin treatment in pre-dialysis patients: results of a multicenter study". Int. J. Artif. Organs., 1998, 21, 12.

[2] Cogan S., Blakemore K.: "Human immunodeficiency virs(perinatal infections)". In: The John Hopkins Manual of Gynecology and Obstetrics Lambrou N. C., Morse A. N., Wallach E. E. (eds). Philadelphia, 1999.

[3] Chudek J., Wiecek A., Kokot F., Grochal A., Switala J., Kanwiszer J.: "Serum erythropoietin concentration in women with uterine or ovarian tumors". Przegl-Lek, 1998, 55, 47.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top