Article Data

  • Views 335
  • Dowloads 109

Reviews

Open Access

Ovarian cancer: State of the art and future directions

  • A. Awada1,*,
  • J. Klastersky1

1Department of Internal Medicine and Medical Oncology, Institut Jules Bordet, Brussels, Belgium

DOI: 10.12892/ejgo200406673 Vol.25,Issue 6,November 2004 pp.673-676

Published: 10 November 2004

*Corresponding Author(s): A. Awada E-mail:

Abstract

The median survival of patients with ovarian cancer has increased steadily, mainly due to a multidisciplinary approach including surgery and chemotherapy. This editorial article summarizes the important messages taken from clinical research performed in this field over the last 15 years. It deals with the following issues: screening, prevention, management of early and advanced disease, maintenance/consolidation therapies and the treatment of relapsing patients. It also gives some future directions with the hope to improve the management and the outcome of this highly lethal disease.

Keywords

Ovarian cancer; Disease management; Chemotherapy

Cite and Share

A. Awada,J. Klastersky. Ovarian cancer: State of the art and future directions. European Journal of Gynaecological Oncology. 2004. 25(6);673-676.

References

[1] Petricoin E.F., Ardekani A.M., Hitt B.A. et al.: "Use of proteomic patterns in serum to identify ovarian cancer". Lancet, 2002, 359, 572.

[2] Kauff N.D., Satagopan J.M., Robson M.E. et al.: "Risk-reducing salpingo-oophorectomy in women with a BRCA 1 or BRCA2 mutation". N. Engl. J. Med., 2002, 346, 1609.

[3] Ozols F.: "Controversies in ovarian cancer". Proceedings of the I 5,h International Congress on Anti-Cancer Treatment, Paris, France, 09-12/02/2004 (educational lecture, 83).

[4] Trimbos J.B., Parmar M., Vergote I. et al.: "International collaborative ovarian neoplasm trial I and adjuvant chemotherapy in ovanan neoplasm trial: t wo parallel randomized pha、e III trials of adjuvant chemotherapy in patients with early-stage ovarian carcinoma" J. Natl. Cancer Inst., 2003, 95, 105.

[5] Mano M., Awada A., Minisini A. et al.: "Remaining controversies in the upfront management of advanced ovarian cancer". Inter. J. Gynaecol. Cancer, 2004 (still in press)

[6] "Paclitaxel plus carboplatin versus standard chemotherapy with either single-agent carboplatin or cyclophosphamide, doxorubicm, and cisplatin in women with ovarian cancer: the ICON3 randomized trial". Lancet, 2002, 360, 505.

[7] Gordon A.N. et al.: "Recurrent epithelial ovarian carcinoma: a randomized phase III study of pegylated liposomal doxorubicin versus topotecan". J. Clin. Oneal., 2001, 19, 3312.

[8] Ferrero J.M. et al.: "Caelyx and paraplatine in patients with advanced ovarian cancer in late relapse: a gineco phase II trial". Abstract, 828, ASCO, 2002.

[9] Parmar M.K., Ledermann J.A., Colombo N. et al.: "Paclitaxel plus platinum-based chemotherapy versus conventional platinum-based chemotherapy in women with relapsed ovarian cancer: the ICON4/AGO-OVAR-2.2 trial". Lancet, 2003, 361, 2099.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top