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Primary ovarian carcinosarcoma: a case report and review of the literature
13rd Department of Obstetrics and Gynaecology, University General Hospital "AITIKON", Athens,Third District National Health System, Athens, Greece
2Department of Obstetrics and Gynaecology, "G. Chatzikosta" General State Hospital, Ioannina, District National Health System, Epirus, Greece
3Department of Internal Medicine, Medical School, University Hospital, Joannina, District National Health System, Epirus, Greece
4Department of Pathology, "G. Chatzikosta" General State Hospital, Joannina, District National Health System, Epirus, Greece
*Corresponding Author(s): M. Varras E-mail: mnvarras@otenet.gr
Primary ovarian carcinosarcoma is characterized by an admixture of malignant epithelial and stromal elements. This neoplasm is extremely rare with fewer than 400 cases reported in the English literature. Its histogenesis, clinical features and optimal treatment remain unclear because of the rarity of primary ovarian carcinosarcoma. This study focuses on the clinical, pathological, immunohistochemical features and survival of a 73-year-old patient with primary ovarian carcinocarcoma. The patient was treated with surgery followed by combined chemotherapy with carboplatin and taxol and assigned to FIGO Stage IIIc. She died from the disease 17 months after surgery. In conclusion, ovarian carcinosarcoma is a very aggressive tumor, especially when it is diagnosed at advanced stage.
Carcinosarcoma; Ovary; Malignant mixed mesodennal; Mixed Miillerian; Tumor; Pathology; Chemotherapy; Survival
M. Varras,Ch. Akrivis,N. Antoniou,C. Tolis,S. Stefanaki,E. Salamalekis. Primary ovarian carcinosarcoma: a case report and review of the literature. European Journal of Gynaecological Oncology. 2004. 25(5);653-656.
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