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Sclerosing stromal cell tumor of the ovary in pregnancy: A case report

  • A. Gurbuz1,*,
  • A. Karateke1
  • C. Kabaca1
  • G. Ozturk Gaziyiz1
  • G. Kir1

1Obstetrics and Gynecology Department, Zeynep Kami/ Women and Children Diseases Education and Research Hospital, Istanbul, Turkey

DOI: 10.12892/ejgo200404534 Vol.25,Issue 4,July 2004 pp.534-535

Published: 10 July 2004

*Corresponding Author(s): A. Gurbuz E-mail:

Abstract

A rare case of benign ovarian stromal cell tumor during pregnancy is presented. Because of a rapidly growing solid ovarian mass, 6 x 7 cm in diameter, a 21-year-old woman at 14 weeks of gestation was explored via laparotomy. Histopathological diagnosis was sclerosing stromal tumor of the ovary. She had no complaint of menstrual irregularities before pregnancy and there was no clinical or hormonal evidence of active androgenic hormone secretion. Immunohistochemical staining showed positive vimentin, smooth-muscle actin and desmin reactions. Sclerosing stromal tumor is a very rare condition in pregnancy and our case is only the eighth case detected during pregnancy according to the literature.

Keywords

Sclerosing stromal tumor; Pregnancy; Ovary

Cite and Share

A. Gurbuz,A. Karateke,C. Kabaca,G. Ozturk Gaziyiz,G. Kir. Sclerosing stromal cell tumor of the ovary in pregnancy: A case report. European Journal of Gynaecological Oncology. 2004. 25(4);534-535.

References

[1] Chalvardjian A., Scully R.E.: "Sclerosing stromal tumors of the ovary". Cancer, I 973, 31 (3), 644.

[2] Young R.H., Scully R.E.: "Sex-cord stromal steroid cell and other ovarian tumors with endocrine, paraendocrine, and paraneoplastic manifestations". In: Kurman R.J. (ed.). Blaustein's Pathology of the Female Genital Tract, 4'" ed. New York Springer-Verlag, 1994, 783.

[3] Duska L.R., Flynn C., Goodman A.: "Masculinizing sclerosmg stromal cell tumor in pregnancy: report of a case and review of the literature". Ew: J. Gynaecol. Oneal., 1998, 19 (5), 441.

[4] Huang S.C., Chen H.C., Chang K.C., Chou C.Y.: "Ascites and elevated androgen level in a pregnant patient with an ovarian sclerosing stromal tumor". J. Formos. Med. Assoc., 2003, 102 (2), 124.

[5] Saitoh A., Tsutsumi Y., Osamura Y., Watenabe K.: "Sclerosing stromal tumor of the ovary. Immunohistochemical and electronmicroscobic demonstration of smooth-muscle differentiation". Arch. Pathol. Lab. Med.,1989, 113 (4), 372.

[6] Docherty M.B., Masson J.C.: "Ovarian fibromas. A clinical and pathological study of two hundred and eighty-three cases". Am. J. Obstet. Gynecol., 1944, 47, 741.

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