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Aggressive angiomyxoma of the vagina: a case report and review of the literature

  • D.J. Papachristou1
  • A. Batistatou1
  • E. Paraskevaidis2
  • N.J. Agnantis1,*,

1Department of Pathology, University Hospital of Ioannina, Ioannina, Greece

2Department of Obstetrics and Gynecology, University Hospital of Ioannina, Ioannina, Greece

DOI: 10.12892/ejgo200404519 Vol.25,Issue 4,July 2004 pp.519-521

Published: 10 July 2004

*Corresponding Author(s): N.J. Agnantis E-mail:

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Abstract

Aggressive angiomyxoma (AA) is a rare mesenchymal tumor of the lower pelvis and genital region, characterized by local infiltration and frequent, even multiple recurrences. In the present paper a case of a small-sized AA of the vagina, in a 55-year-old woman is reported. We describe the histological appearance and the immunohistochemical phenotype of this tumor and discuss its differential diagnosis from other mesenchymal lesions occurring in the pelvic and genital region. Furthermore, we attempt to enlighten the possible mechanisms that govern the pathogenesis and the biological behavior of this "mysterious" neoplasm.

Keywords

Aggressive angiomyxoma; Immunohistochemistry; Behavior; Treatment; Prognosis

Cite and Share

D.J. Papachristou,A. Batistatou,E. Paraskevaidis,N.J. Agnantis. Aggressive angiomyxoma of the vagina: a case report and review of the literature. European Journal of Gynaecological Oncology. 2004. 25(4);519-521.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200404519

References

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[8] Chan Y.M., Hon E., Ngai S.W., Ng T.Y., Wong L.C., Chan l.M.: "Aggressive angiomyxoma in females: is radical resection the only option?“ Acta Obstet. Gynecol. Scand., 2000, 79 (3), 216.

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[11] Fine B.A., Munoz A.K., Craig E.L., Gershenson D.M.: "Pnmary medical management of recurrent aggressive angiomyxoma of the vulva with a gonadotropin-releasing hormone agonist". Gynecol Oncol., 2000, 81, 120.

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