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A case of rhabdomyosarcoma of the vagina in an elderly woman

  • Y. Suzuki1,*,
  • H. Sakurai1
  • M. Hasegawa1
  • T. Kanuma2
  • A. Segawa3
  • T. Nakano1

1Department of Radiation Oncology, Gunma University, Graduate School of Medicine, Gunma, Japan

2Department of Obstetrics and Gynecology, Gunma University, Graduate School of Medicine, Gunma, Japan

3Departlnent of Pathology II, Gunma University, Graduate School of Medicine, Gunma, Japan

DOI: 10.12892/ejgo200404509 Vol.25,Issue 4,July 2004 pp.509-511

Published: 10 July 2004

*Corresponding Author(s): Y. Suzuki E-mail:

PDF (1.64 MB)

Abstract

Most rhabdomyosarcomas of the vagina (RMSV) occur in infants and children up to six years old. RMSV in elderly patients is extremely rare. We report a case of a 70-year-old woman with RMSV. She had received surgery for uterine endometrial cancer one year before and a vaginal polypoid tumor was noted during routine follow-up vaginal examination. She was referred to our department for radiation therapy following partial tumorectomy of the lesion. She was given three sessions of intra-vaginal radiation therapy, once a week with 6 Gy at 7.5 mm below the vaginal surface and external irradiation of 50 Gy to the pelvis. However, paraaortal lymph node metastasis developed during initial radiation therapy. Furthermore, multiple bone metastases appeared at the completion of the radiation therapy. Six months after initial treatment the patient died from progression of the disease. Autopsy demonstrated small residual tumor at the primary site as well as multiple systemic metastases.

Keywords

Rhabdomyosarcoma, Vagina, Elderly woman, Radiation therapy

Cite and Share

Y. Suzuki,H. Sakurai,M. Hasegawa,T. Kanuma,A. Segawa,T. Nakano. A case of rhabdomyosarcoma of the vagina in an elderly woman. European Journal of Gynaecological Oncology. 2004. 25(4);509-511.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200404509

References

[1] Grogg D.B.: "P elvic neoplasms in children". J. Surg. Oneal., 2001, 77, 65.

[2] Shy S.W., Lee W.H., Chen D., Ho S.Y.: "Rhabdomyosarcoma of the vagina in a post menopausal woman". Gynecol. Oneal., 1995, 58, 395.

[3] Hilgers R.D., Malkasian G.D., Soule E.H.: "Embryonal rhabdomyosarcoma (botryoid type) of the vagina". Am. J. Obstet. Gynecol., 1970, 107, 484.

[4] Andassy R.J., Hays D.M., Raney R.B., Wiener E.S., Lawrence W., Lobe T.E. et al.: "Conservative surgical management of vaginal and vulvar pedatiric rhabdomyosarcoma: a report from the intergroup rhabdomyosarcoma study III". J. Pediatr. Surg., 1995, 30, 1034.

[5] Maurer H.M.: "The Intergroup Rhabdomyosarcoma Study (NIH): Objectives and clinical staging classification". J. Pediatr. Surg., 1975, 10, 977.

[6] Dias P., Kumar P., Marsden H.B., Morris-Jones P.H., Birch J., Kumar S.: "Evaluation of desmin as a diagnostic and prognostic marker of childhood rhabdomyosarcomas and embryonal sarcomas". Br. J. Cancer, 1987, 56, 361.

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