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Endometrioid adenocarcinoma arising in endometriosis foci six years after estrogen replacement therapy: a case report

  • A. Areia1,*,
  • V. Sousa2
  • C. Frutuoso1
  • I. Dias1
  • M.I. Martins2
  • C.F. de Oliveira1

1Department of Gynecology, Portugal

2Department of Pathology, Coimbra University Hospital, Portugal

DOI: 10.12892/ejgo200402255 Vol.25,Issue 2,March 2004 pp.255-256

Published: 10 March 2004

*Corresponding Author(s): A. Areia E-mail:

Abstract

We present a case of a 53-year-old woman who developed an endometrioid adenocarcinoma six years after total abdominal hysterectomy (TAH) and bilateral salpingo-oophorectomy (BSO), who was on estrogenic-only hormone replacement therapy (HRT).

Keywords

Endometrioid adenocarcinoma; Endometriosis foci; Estrogenic replacement therapy

Cite and Share

A. Areia,V. Sousa,C. Frutuoso,I. Dias,M.I. Martins,C.F. de Oliveira. Endometrioid adenocarcinoma arising in endometriosis foci six years after estrogen replacement therapy: a case report. European Journal of Gynaecological Oncology. 2004. 25(2);255-256.

References

[1] "Oestrogen therapy and endometrial cancer". Lancet, 1979, 26, I (8126), 1121.

[2] Thomas E.J., Campbell LG.: "Evidence that endometriosis behaves in a malignant manner". Gynecol. Obstet. Invest., 2000, 50 (suppl. 1), 2.

[3] Debus G., Schuhmacher I.: "Endometrial adenocarcinoma arising during estrogenic treatment 17 years after total abdominal hysterectomy and bilateral salpingo-oophorectomy: a case report". Acta Obstet. Gynecol. Scand., 2001, 80 (6), 589.

[4] Brinton L.A., Gridley G., Perrson I., Baron J., Bergqvist A.: "Cancer risk after hospital discharge diagnosis of endometriosis". Am. J. Obstet. Gynecol., 1997, 176, 572.

[5] Reimnitz C., Brand E., Nieberg R.K., Hacker N.F.: "Malignancy arising in endometriosis associated with unopposed estrogen replacement". Obstet. Gynecol., 1988, 71, 444.

[6] Brooks J., Wheeler J.: "Malignancy arising in extragonadal endometriosis". Cancer, 1977, 40, 3065.

[7] Eckert R., Eckert R.: "Adenocarcinoma arising in endometriosis". Am. Fam. Physician, 2000, 62 (4), 734.

[8] Sampson J.A.: "Endometrial carcinoma of the ovary arising m endometrial tissue in that organ". Arch. Surgery, 1925, 10, 1.

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