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Successful treatment with weekly paclitaxel in a patient with recurrent endornetrial cancer. A case report

  • S-J Chang1
  • T-C Chen2
  • T-Y Wang3
  • C-Y Hsu4
  • H-S Chen2
  • Y-C Yang5,*,

1Fellow, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taiwan

2Attending, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taiwan

3Lecturer, Mackay Junior college of Nursing, Attending, Department of Pathology, Mackay Memorial Hospital, Taiwan

4Attending, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taiwan

5Assoc. Prof, Taipei Medical University, Chairman, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital Taipei, Taiwan

DOI: 10.12892/ejgo200305377 Vol.24,Issue 5,September 2003 pp.377-378

Published: 10 September 2003

*Corresponding Author(s): Y-C Yang E-mail:

Abstract

The best treatment for recurrent endometrial cancer is still uncertain, although weekly paclitaxel has shown some promise in the management of this disease. In this report we present a patient with recurrent endometrial cancer treated with weekly paclitaxel. Serial power Doppler angiography was used to assess the effects of therapy. The response was good, suggesting that recurrent endometrial cancer may be successfully treated with weekly paclitaxel and effectively monitored with power Doppler angiography.

Keywords

Recurrent endometrial cancer; Weekly paclitaxel

Cite and Share

S-J Chang,T-C Chen,T-Y Wang,C-Y Hsu,H-S Chen,Y-C Yang. Successful treatment with weekly paclitaxel in a patient with recurrent endornetrial cancer. A case report. European Journal of Gynaecological Oncology. 2003. 24(5);377-378.

References

[1] Elit L., Hirte H.: "Current status and future innovations of hormonal agents, chemotherapy and investigational agents in endometrial cancer". Cun: Opin. Obstet. Gynecol., 2002, 14, 67.

[2] Anderson H., Horvath G., Mellqvist L., Westberg R.:'Taxol given weekly in advanced previously treated ovarian carcinoma: a pilot study". Int. J. Gynecol. Cancer, 1997, 7, 262.

[3] Klassen U., Wilke H., Strumberg D., Eberhardt W., Korn M., Seeber S.: "Phase l study with a weekly I h infusion of paclitaxel in heavily pretreated patients with metastatic breast and ovarian cancer". Eur. J. Cancer, 1996, 32, 547.

[4] Eisenhauer E.A., ten Bokkel Huinink W.W., Swenerton K.D., Gianni L., Myles J., van der Burg M.E. et al.: "European-Canadian randomized trial of paclitaxel in relapsed ovarian cancer high-dose versus low-dose and long versus short infusion". J. Clin. Oncol., 1994, 12, 2654.

[5] T savaris N.B., Kosrnas C.: "Risk of severe acute hypersensitivity reactions after rapid paclitaxel infusion of less than 1-h duration" Cancer Chemother. Pharmacol., 1998, 42, 509

[6] Ota S., Sugiyama T., Ushijima K., Kornai K., Fujiyoshi K., Hirai N. et al.: "Successful treatment of two patients with recurrent endornetrial cancer by weekly paclitaxel". Cancer lett., 2000, 160, 9.

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