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Original Research

Open Access

Associations between tumor diameter and prognostic variables of epithelial ovarian cancer

  • T. Nakanishi1,*,
  • A. Nawa1
  • Y. Niwa1
  • S. Nakamura2
  • K. Kuzuya1

1Department of Gynecology, Japan

2Department of Pathology and Clinical Laboratory,Aichi Cancer Center Hospital, Nagoya, Japan

DOI: 10.12892/ejgo20030145 Vol.24,Issue 1,January 2003 pp.45-47

Published: 10 January 2003

*Corresponding Author(s): T. Nakanishi E-mail:

Abstract

Purpose: Associations of tumor diameter in epithelial ovarian cancer with clinical and pathological prognostic variables were investigated.

Methods: The clinical and pathological records of 233 patients diagnosed with epithelial ovarian cancer and treated at Aichi Cancer Center were studied.

Results: Tumor diameters of 44 patients (18.9%) were < 5 cm, 90 (38.6%) were 5-10 cm, and 99 (42.5%) were > 10 cm. While 90.9% (40/44) of < 5 cm tumors presented with FIGO stage III-IV, 40.4% (40/99) of > 10 cm tumors were advanced. Intra-abdominal disease was also significantly associated with tumor diameter, although differences among lymph-node status were not significant. The incidence of serous and endometrioid adenocarcinoma in < 5 cm tumors were 75.0% (33/44) and 11.4% (5/44), respectively, while those of > 10 cm tumor were 32.3% (32/99) and 17.2% (17/99). Multivariate analysis revealed that tumor diameter was not an independent prognostic variable.

Conclusion: Tumor diameter of ovarian cancer is associated closely with histological subtypes and stage of disease, especially intra-abdominal disease.

Keywords

Ovarian cancer; Tumor diameter

Cite and Share

T. Nakanishi,A. Nawa,Y. Niwa,S. Nakamura,K. Kuzuya. Associations between tumor diameter and prognostic variables of epithelial ovarian cancer. European Journal of Gynaecological Oncology. 2003. 24(1);45-47.

References

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