Article Data

  • Views 209
  • Dowloads 124

Original Research

Open Access

Associations between tumor diameter and prognostic variables of epithelial ovarian cancer

  • T. Nakanishi1,*,
  • A. Nawa1
  • Y. Niwa1
  • S. Nakamura2
  • K. Kuzuya1

1Department of Gynecology, Japan

2Department of Pathology and Clinical Laboratory,Aichi Cancer Center Hospital, Nagoya, Japan

DOI: 10.12892/ejgo20030145 Vol.24,Issue 1,January 2003 pp.45-47

Published: 10 January 2003

*Corresponding Author(s): T. Nakanishi E-mail:

Abstract

Purpose: Associations of tumor diameter in epithelial ovarian cancer with clinical and pathological prognostic variables were investigated.

Methods: The clinical and pathological records of 233 patients diagnosed with epithelial ovarian cancer and treated at Aichi Cancer Center were studied.

Results: Tumor diameters of 44 patients (18.9%) were < 5 cm, 90 (38.6%) were 5-10 cm, and 99 (42.5%) were > 10 cm. While 90.9% (40/44) of < 5 cm tumors presented with FIGO stage III-IV, 40.4% (40/99) of > 10 cm tumors were advanced. Intra-abdominal disease was also significantly associated with tumor diameter, although differences among lymph-node status were not significant. The incidence of serous and endometrioid adenocarcinoma in < 5 cm tumors were 75.0% (33/44) and 11.4% (5/44), respectively, while those of > 10 cm tumor were 32.3% (32/99) and 17.2% (17/99). Multivariate analysis revealed that tumor diameter was not an independent prognostic variable.

Conclusion: Tumor diameter of ovarian cancer is associated closely with histological subtypes and stage of disease, especially intra-abdominal disease.

Keywords

Ovarian cancer; Tumor diameter

Cite and Share

T. Nakanishi,A. Nawa,Y. Niwa,S. Nakamura,K. Kuzuya. Associations between tumor diameter and prognostic variables of epithelial ovarian cancer. European Journal of Gynaecological Oncology. 2003. 24(1);45-47.

References

[1] Hoskins W. J., McGuire W. P., Brady M. F., Homesley H. D., Creasman W. T., Berman M. et al.: "The effect of diameter of largest residual disease on survival after primary cytoreductive surgery in patients with suboptimal residual epithelial ovarian carcinoma". Am. J. Obstet. Gynecol., 1994, 170, 974.

[2] Makar A. P., Baekelandt M., Trope C. G., Kristensen G. B.: "The prognostic significance of residual disease, FIGO substage, tumor histology, and grade in patients with FIGO stage III ovarian cancer". Gynecol. Oncol., 1995, 55, 175.

[3] Stratton J. F., Pharoah P., Tidy J. A., Paterson M. E.: "An analysis of ovarian tumor diameter and survival". Int. J. Gynecol. Cancer , 2000, 10, 449.

[4] Jacobs I. J., Skates S. J., MacDonald N., Menon U., Rosenthal A N., Davies A. P. et al.: "Screening for ovarian cancer: a pilot randomised controlled trial". Lancet, 1999, 353, 1207.

[5] Klaric P., Zovak M., Brezovec-Cvetnic B., Pirkic A., Tuckar N.: "Giant mucinous malignant ovarian tumor". Zentralhl. Gynakol., 1999, 121, 298.

[6] Feuer G. A., Shevchuk M., Calanog A.: "Normal-sized ovary carcinoma syndrome". Ohstet. Gynecol., 1989, 73, 789.

[7] Cannistra S. A.: "Cancer of the ovary". New Engl. J. Med., 1993, 329, 1550.

[8] Omura G. A., Brady M. F., Homesley H. D., Yordan E., Major F J., Buchsbaum H.J. et al.: "Long-term follow-up and prognostic factor analysis in advanced ovarian carcinoma: the Gynecologic Oncology Group experience". J. Clin. Oneal., 1991, 9, 1138.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top