Article Menu

Export Article

More by Authors Links

Article Data

  • Views 281
  • Dowloads 146

Original Research

Open Access

Chlamydia trachomatis infection in women with CIN and invasive uterine cervix cancer. Significance of hormonal status

  • J. Markowska1,*,
  • N. Fischer2
  • Z. Fischer2
  • J.B. Warchol3

1Chair of Oncology, Poland

2Departments of Gynecology and Obstetrics, Holy Family Clime, Poland

3Chair of Radiology and Biology Faculty of Medicine, K.Marcinkowski University School of Medicine, Poznan, Poland

DOI: 10.12892/ejgo200206511 Vol.23,Issue 6,November 2002 pp.511-513

Published: 10 November 2002

*Corresponding Author(s): J. Markowska E-mail:

PDF (301.86 kB)

Abstract

In women with CIN at fertile age and those over 50 years of age, EGFR expression is lower in the presence of Chlamydia trachomatis (Cht) infection. In all Cht infected women over 50 years of age expression of Ki 67 is higher; the increase is significant among women with invasive carcinoma. In these groups of women with CIN and invasive carcinoma TGF-alpha expression is insignificantly augmented. Chronic Cht infection is associated with cervical hypertrophy.

Keywords

Cht infection; CIN; Cervical cancer; Hormonal status

Cite and Share

J. Markowska,N. Fischer,Z. Fischer,J.B. Warchol. Chlamydia trachomatis infection in women with CIN and invasive uterine cervix cancer. Significance of hormonal status. European Journal of Gynaecological Oncology. 2002. 23(6);511-513.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200206511

References

[1] Anttila T., Saikku P., Koskela P., et al.: "Serotypes of Chlamydia trachomatis and risk for development of cervical squamous cell carcinoma". J.A.M.A., 2000, 285, 47.

[2] Beatty W. L., Morrison R. P., Byrne G. L.: "Persistent Chlamydiae". Microbial. Rev., 1994, 58, 686.

[3] Blum H., Benaim J.: "Activities of a family planning chmc rncorporated to a public medical service over a 4-year period". Rev. Fr. Gynecol. Obstet., 1991, 86 (5), 381.

[4] Bose S. K., Goswami P. C.: "Enhancement of adherence and growth of Chlamydia trachomatis by estrogen treatment of HeLa cells". Inject. Immun., 1986, 53 (3), 646.

[5] Koivisto A. L., lsoacho R., von Hertzen L., et al.: "Chlamydial antibodies in an elderly Finnish population". Scand. J. Infect. Dis., 1999, 31 (2), 135.

[6] Koskela P., Anttila T., Bjiirge T., et al.: "Chlamydia trachomatis infection as a risk for invasive cervical carcinoma". Int. J. Cancer, 2000, 85, 35.

[7] Markowska J., Fischer N., Filas V., et al.: "The role of Chlamydia trachomatis infection in cervical cancer development". Eur. J. Gynaecol. Oneal., 1999, 20 (2), 144.

[8] Puolakkainen M., Vesterinen E., Purola E., et al.: "Persistence of chlamydia] antibodies after pelvic inflammatory disease". J. Clin Microbial., 1986, 23, 924.

[9] Suchet H.: "Hormonal contraception and pelvic inflammatory disease". Ew: J. Contracept. Reprod. Health Care, 1997, 4, 267.

[10] Wallin K. L., Wiklund F., Angstrom T., et al.:'Type-specific persistence of human papilloma virus DNA before the development of invasive cervical cancer". N. Engl. J. Med., 1999, 341, 1633.

[11] Zdrodowska Stefanow B., Ostaszewska J.: "Chlamydia trachomatis- infections in humans (in Polish)", 2000.

[12] Zur Hausen H.: "Cervical carcinoma and human papilloma virus: on the road to preventing a major human cancer". J. Natl. Cancer Inst., 2001, 93 (4), 252.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top