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Granular cell tumor of the breast: a rare lesion resembling breast cancer

  • J. Gogas1
  • C. Markopoulos1
  • E. Kouskos1,*,
  • H. Gogas1
  • D. Mantas1
  • Z. Antonopoulou1
  • K. Kontzoglou1

1Breast Unit - 2"" Department of Propedeutic Surgery, Athens University Medical School - "Laiko" General Hospital, Athens, Greece

DOI: 10.12892/ejgo200204333 Vol.23,Issue 4,July 2002 pp.333-334

Published: 10 July 2002

*Corresponding Author(s): E. Kouskos E-mail:

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Abstract

Granular cell tumor (GCT) is an uncommon, usually benign tumor that occasionally involves the breast. It is possibly of neural origin (Schwann cells) and usually occurs in premenopausal black women. Physical examination, mammographic, ultrasonographic findings and pathologic examination may suggest breast malignancy. Positive immunohistochemical staining of the cells for S-100 protein, NSE, and CEA is indicative of GCT. Surgical treatment of choice is wide local excision. We report a case of granular cell tumor of a female breast. A 52-yr-old white woman had a palpable mass close to her right axilla. Computer tomography (CT) showed a 3.74 cm mass in the mammary tail of Spencer. The findings were suspicious for malignancy and the lesion was widely resected. Pathologic examination showed granular cell tumor.

Keywords

Granular cell tumor; Breast; Benign neoplasm; Immunohistochemistry


Cite and Share

J. Gogas,C. Markopoulos,E. Kouskos,H. Gogas,D. Mantas,Z. Antonopoulou,K. Kontzoglou. Granular cell tumor of the breast: a rare lesion resembling breast cancer. European Journal of Gynaecological Oncology. 2002. 23(4);333-334.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200204333

References

[1] Abrikosoff A.: "Weitere untersuchungen uber muoblastenmyome" Virchow. Arch. Path. Anat., 1931, 280, 723.

[2] De May R. M., Kay S.: "Granular cell tumor of the breast". Pathol. Ann., 1984, 19, 121.

[3] Lee S., Morimoto K., Katsuragi K., Hosono M., Wakasa K., Kinoshita H.: "Granular cell tumor of the male breast: report of a case" Surg. Today, 2000, 30, 658.

[4] Krouse T., Mobini J.: "Multifocal granular cell myoblastoma" Arch. Pathol., 1973, 96, 95.

[5] Gibbons D., Leitch M., Coscia J., Lindberg G., Molberg K., Ashfaq R., Saboorian M. H.: "Fine needle aspiration cytology and histologic findings of granular cell tumor of the breast: review of 19 cases with clinical/radiologic co订elation". Breast. J., 2000, 6, 27.

[6] Hann H.J., Iglesias J., Flenker H., Kreuzer G.: "OCT in differential diagnosis of tumors of the breast. The role of FNA cytology" Pathol. Res. Pract., 1992, 188, 1091.

[7] Gordon A., Fisher C., Palmer B., Greening W." Granular cell tumor of the breast". Eur. J. Surg. Oneal., 1985, 11, 269.

[8] Chetty R., Kalan M. R.: "Malignant GCT of the breast". J. Surg Oncol., 1992, 49, 135.

[9] Tai G.. D'Costa H., Lee D、Watkins R. M., Jones P.: "Case report coincident GCT of the breast with invasive ductal carcinoma". Br. J. Radiol., 1995, 68, 1034.

[10] Miller J. A., Karckik T. J., Karimi S.: "Granular cell tumor of the breast: definite diagnosis by sonographically guided percutaneous biopsy". J. Clin. Ultrasound, 2000, 28, 89.

[11] Okada K., Ozeki K., Isomoto I., Matsuo T., Mochinaga N.: "Granular cell tumor of the breast: a case report describing dynamic MR mammography". Breast Cancer, 1998, 25, 179.

[12] Horiguchi J., Iino Y., Takei H., Maemura M., Koibuchi Y., Horii Y. et al.: "Granular cell tumor of the breast diagnosed by core needle biopsy: a case report". Breast Cancer, 1999, 25, 69.

[13] Regalado J., Sittler S.: "GCT of the male breast: a report of three cases and a review of the literature". Breast Dis., 1996, 9, 235.

[14] Uzoary I., Filter B.: "Malignant GCT". Arch. Pathol. Lab. Med., 1992, 116, 206.

[15] Lelle R. J., Park H.: "Benign GCT mimicking carcinoma of the breast: report of a case". Eur. J. Gynaecol. Oneal., 1992, 13, 390.

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