Article Menu

Export Article

More by Authors Links

Article Data

  • Views 221
  • Dowloads 128

Case Reports

Open Access

Granular cell tumor of the breast: a rare lesion resembling breast cancer

  • J. Gogas1
  • C. Markopoulos1
  • E. Kouskos1,*,
  • H. Gogas1
  • D. Mantas1
  • Z. Antonopoulou1
  • K. Kontzoglou1

1Breast Unit - 2"" Department of Propedeutic Surgery, Athens University Medical School - "Laiko" General Hospital, Athens, Greece

DOI: 10.12892/ejgo200204333 Vol.23,Issue 4,July 2002 pp.333-334

Published: 10 July 2002

*Corresponding Author(s): E. Kouskos E-mail:

PDF (1.73 MB)

Abstract

Granular cell tumor (GCT) is an uncommon, usually benign tumor that occasionally involves the breast. It is possibly of neural origin (Schwann cells) and usually occurs in premenopausal black women. Physical examination, mammographic, ultrasonographic findings and pathologic examination may suggest breast malignancy. Positive immunohistochemical staining of the cells for S-100 protein, NSE, and CEA is indicative of GCT. Surgical treatment of choice is wide local excision. We report a case of granular cell tumor of a female breast. A 52-yr-old white woman had a palpable mass close to her right axilla. Computer tomography (CT) showed a 3.74 cm mass in the mammary tail of Spencer. The findings were suspicious for malignancy and the lesion was widely resected. Pathologic examination showed granular cell tumor.

Keywords

Granular cell tumor; Breast; Benign neoplasm; Immunohistochemistry


Cite and Share

J. Gogas,C. Markopoulos,E. Kouskos,H. Gogas,D. Mantas,Z. Antonopoulou,K. Kontzoglou. Granular cell tumor of the breast: a rare lesion resembling breast cancer. European Journal of Gynaecological Oncology. 2002. 23(4);333-334.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200204333

References

[1] Abrikosoff A.: "Weitere untersuchungen uber muoblastenmyome" Virchow. Arch. Path. Anat., 1931, 280, 723.

[2] De May R. M., Kay S.: "Granular cell tumor of the breast". Pathol. Ann., 1984, 19, 121.

[3] Lee S., Morimoto K., Katsuragi K., Hosono M., Wakasa K., Kinoshita H.: "Granular cell tumor of the male breast: report of a case" Surg. Today, 2000, 30, 658.

[4] Krouse T., Mobini J.: "Multifocal granular cell myoblastoma" Arch. Pathol., 1973, 96, 95.

[5] Gibbons D., Leitch M., Coscia J., Lindberg G., Molberg K., Ashfaq R., Saboorian M. H.: "Fine needle aspiration cytology and histologic findings of granular cell tumor of the breast: review of 19 cases with clinical/radiologic co订elation". Breast. J., 2000, 6, 27.

[6] Hann H.J., Iglesias J., Flenker H., Kreuzer G.: "OCT in differential diagnosis of tumors of the breast. The role of FNA cytology" Pathol. Res. Pract., 1992, 188, 1091.

[7] Gordon A., Fisher C., Palmer B., Greening W." Granular cell tumor of the breast". Eur. J. Surg. Oneal., 1985, 11, 269.

[8] Chetty R., Kalan M. R.: "Malignant GCT of the breast". J. Surg Oncol., 1992, 49, 135.

[9] Tai G.. D'Costa H., Lee D、Watkins R. M., Jones P.: "Case report coincident GCT of the breast with invasive ductal carcinoma". Br. J. Radiol., 1995, 68, 1034.

[10] Miller J. A., Karckik T. J., Karimi S.: "Granular cell tumor of the breast: definite diagnosis by sonographically guided percutaneous biopsy". J. Clin. Ultrasound, 2000, 28, 89.

[11] Okada K., Ozeki K., Isomoto I., Matsuo T., Mochinaga N.: "Granular cell tumor of the breast: a case report describing dynamic MR mammography". Breast Cancer, 1998, 25, 179.

[12] Horiguchi J., Iino Y., Takei H., Maemura M., Koibuchi Y., Horii Y. et al.: "Granular cell tumor of the breast diagnosed by core needle biopsy: a case report". Breast Cancer, 1999, 25, 69.

[13] Regalado J., Sittler S.: "GCT of the male breast: a report of three cases and a review of the literature". Breast Dis., 1996, 9, 235.

[14] Uzoary I., Filter B.: "Malignant GCT". Arch. Pathol. Lab. Med., 1992, 116, 206.

[15] Lelle R. J., Park H.: "Benign GCT mimicking carcinoma of the breast: report of a case". Eur. J. Gynaecol. Oneal., 1992, 13, 390.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top