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Melanocytic dysplasia and multiple melanoma of the vulva
1Department of Dermatology, Italy
2Pathology,Catholic University Medical School, Rome, Italy
3Department of Gynaecology, Columbus Medical Centre, Rome, Italy
*Corresponding Author(s): G. Massi E-mail:
We report a case of a 24-year-old woman with multiple pigmented lesions on her vulva. Histologically the lesions showed a heterogeneous pattern: the majority consisted of melanoma in situ and invasive melanoma; in a few lesions a much less clear-cut picture was found with only melanocytic dysplasia of various degrees. Our case shows the relationship between anomalous melanocytic proliferation of the vulva and vulvar melanoma and underlines the necessity of a thorough check of all melanocytic vulvar lesions also in young patients.
Vulvar multiple melanoma; Vulvar melanocytic dysplasia; Melanoma precursors
G. Fabrizi,G. F. Zannoni,L. I. Lopez,G. Massi. Melanocytic dysplasia and multiple melanoma of the vulva. European Journal of Gynaecological Oncology. 2002. 23(4);323-324.
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[2] Tasseron E. W. K., Van der Esch E. P., Hart A. A. M. et al.: "A Chnicopathological Study of 30 melanomas of the vulva". Gynecol Oncol., 1992, 42, 170.
[3] Podczaski E.,A rthur A. B. D.,K aminsky P. et al.: "A patient with multiple malignant melanoma of the lower genital tract". Gynecol Oneal., 1990, 37, 422.
[4] Kerley S. W., Blute L. M., Keeney L. G.: "Multifocal malignant melanoma arising in vesicovaginal melanosis". Arch. Pathol. Lab Med., 1991, 115, 950.
[5] Ohashi K., Kasuga T., Tanaka N. et al.: "Malignant melanoma of the oral cavity: Heterogeneity of pathological and clinical features". Virchows Archiv. a Pathol. Anat., 1992, 420, 43.
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