Article Menu

Export Article

More by Authors Links

Article Data

  • Views 242
  • Dowloads 108

Case Reports

Open Access

Ovarian capillary hemangioma and stromal luteinization: a case study with hormonal receptor evaluation

  • D. Miliaras1,3,*,
  • S. Papaemmanouil1
  • G. Blatzas2

1Department of Pathology, Greece

2Division of Surgery, General Clinic of Thessaloniki, Greece

3Laboratory of Histology and Embryology, Medical Faculty, Aristotelian University, Thessaloniki, Greece

DOI: 10.12892/ejgo200105369 Vol.22,Issue 5,September 2001 pp.369-371

Published: 10 September 2001

*Corresponding Author(s): D. Miliaras E-mail:

PDF (3.81 MB)

Abstract

Background: Ovarian hemangiomas are rare tumors, most of them asymptomatic, and of the cavernous type. Six of the reported cases were accompanied by stromal luteinization. There is a debate whether these luteinized cells promote the growth of the vascular lesion or just represent a stromal reaction.

Case: A 71-year-old female was incidentally found to have a small capillary hemangioma in her left ovary, surrounded by a rim of luteinized stromal cells. Immunohistochemical investigation revealed the presence of estrogen and progesterone receptors in the endothelial cells of the lesion.

Conclusion: Our histological and immunohistochemical findings, as well as data from the literature, support the view that at least some vascular lesions may result from hormonal stimulation.

Cite and Share

D. Miliaras,S. Papaemmanouil,G. Blatzas. Ovarian capillary hemangioma and stromal luteinization: a case study with hormonal receptor evaluation. European Journal of Gynaecological Oncology. 2001. 22(5);369-371.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200105369

References

[1] Savargaonkar P.R., Wells S., Graham I., Buckley C.H.: "Ovanan hemangiomas and stromal luteinization". Histopathology, 1994, 25, 185.

[2] Carder P. J., Goudlesbrough D. R.: "Ovarian hemangiomas and stromal luteinization". Histopathology, 1995, 26,585.

[3] Gehring P. A., Fowler W. C., Lininger R. A.: "Ovarian capillary hemangioma presenting as an adnexal mass with massive ascites and elevated CA-125". Gynecol. Oneal., 2000, 76, 130.

[4] Yamawaki T., Hirai Y.,Takeshima N., Hasumi K.: "Ovarian hemangioma associated with concominant stromal luteinization and ascites". Gynecol. Oncol., 1996, 61, 438.

[5] Lawhead R. A., Copeland L. J., Edwards C. L.: "Bilateral ovanan hemangiomas associated with diffuse abdominopelvic hemangiomatosis". Ohstet. Gynecol., 1985, 65, 597.

[6] Dean P. J., Haggitt R. C., O'Hara C. J.: "Malignant epithelioid hemangioendothelioma of the liver in young women: relationship to oral contraceptive use". Am. J. Surf?. Pathol., 1985, 9, 695.

[7] Makela S.,S avolainen H.,A avik E.,M yllarniemi M.,S trauss L., Ta skinen E. et al.: "Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors a and B". Proc. Natl. Acad. Sci. U.S.A., 1999, 96, 7077.

[8] Mueller M. D.,V igne J.-L.,M inchenko A.,L ebovic D. I., Leitman D. C., Taylor R. N.: "Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors a and B Proc. Natl. Acad. Sci. U.S.A., 2000, 97, 10972.

[9] Russell K. S., Haynes M. P., Sinha D., Clerisme E., Bender J. R.: "Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling". Proc Natl. Acad. Sci. U.S.A., 2000, 97, 5930.

[10] Scully R.E.: "Ovarian tumours with functioning stroma". In: Fox H. (ed.): Obstetrical & Gynaecological Pathology, 3nd ed. Churchill Livingstone, Edinburgh, 1987, 724.

Abstracted / indexed in

Science Citation Index Expanded (SciSearch) Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,500 of the world’s most impactful journals across 178 scientific disciplines. More than 53 million records and 1.18 billion cited references date back from 1900 to present.

Biological Abstracts Easily discover critical journal coverage of the life sciences with Biological Abstracts, produced by the Web of Science Group, with topics ranging from botany to microbiology to pharmacology. Including BIOSIS indexing and MeSH terms, specialized indexing in Biological Abstracts helps you to discover more accurate, context-sensitive results.

Google Scholar Google Scholar is a freely accessible web search engine that indexes the full text or metadata of scholarly literature across an array of publishing formats and disciplines.

JournalSeek Genamics JournalSeek is the largest completely categorized database of freely available journal information available on the internet. The database presently contains 39226 titles. Journal information includes the description (aims and scope), journal abbreviation, journal homepage link, subject category and ISSN.

Current Contents - Clinical Medicine Current Contents - Clinical Medicine provides easy access to complete tables of contents, abstracts, bibliographic information and all other significant items in recently published issues from over 1,000 leading journals in clinical medicine.

BIOSIS Previews BIOSIS Previews is an English-language, bibliographic database service, with abstracts and citation indexing. It is part of Clarivate Analytics Web of Science suite. BIOSIS Previews indexes data from 1926 to the present.

Journal Citation Reports/Science Edition Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and provide readers a transparent and publisher-neutral data & statistics information about the journal.

Submission Turnaround Time

Conferences

Top