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Extragonadal retroperitoneal endodermal sinus tumor in an eight-month-old female infant

  • J. Manavis1,*,
  • G. Alexiadis1
  • M. Lambropoulou2
  • S. Deftereos1
  • P. Argyropoulou1
  • A. Giatromanolaki2
  • E. Sivridis2

1Department of Radiology, Greece

2Department of Pathology, Democritus University of Thrace, Alexandroupolis, Greece

DOI: 10.12892/ejgo200105345 Vol.22,Issue 5,September 2001 pp.345-346

Published: 10 September 2001

*Corresponding Author(s): J. Manavis E-mail:

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Abstract

We describe a rare case of an extragonadal retroperitoneal endodermal sinus (yolk sac) tumor in the minor pelvis. Radiologic investigation, which included abdominal ultrasound and computed tomography (CT), showed a large soft tissue mass occupying the pelvic cavity. Radionuclide bone scans demonstrated bone metastases. The serum alpha fetoprotein was elevated. Pathologic examination of the surgical specimen revealed extragonadal yolk sac tumor. Immunohistochemically, the tumor was positive for a-feto-protein and cytokeratins. After postoperative combination therapy, follow-up CT showed decreasing tumoral disease, while serum alpha fetoprotein returned to normal.

Keywords

Endodermal sinus tumor; Yolk sac tumor; CT; Ultrasound; a-fetoprotein; Retroperitoneal

Cite and Share

J. Manavis,G. Alexiadis,M. Lambropoulou,S. Deftereos,P. Argyropoulou,A. Giatromanolaki,E. Sivridis. Extragonadal retroperitoneal endodermal sinus tumor in an eight-month-old female infant. European Journal of Gynaecological Oncology. 2001. 22(5);345-346.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200105345

References

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