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Bullous pemphigoid masquerading as acute radiation dermatitis: Case report

  • S. K. Parikh1,*,
  • A. Ravi2
  • D. Yi-Shin Kuo3
  • D. Nori1

1Weill Medical College of Cornell University, New York, USA

2Resident, Radiation Oncology, New York Presbyterian Hospital (Cornell), New York, USA

3Attending Gynecologic Oncologist, The New York Hospital Medical Center of Queens, Flushing, New York, USA

DOI: 10.12892/ejgo200105322 Vol.22,Issue 5,September 2001 pp.322-324

Published: 10 September 2001

*Corresponding Author(s): S. K. Parikh E-mail:

Abstract

We report the first case of bullous pemphigoid complicating radiation therapy for vulvar cancer. Shortly after completion of postoperative radiation therapy for a TIN1 vulvar carcinoma, the patient presented with a rash that started within, but continued to extend, well beyond the radiation field. A biopsy of the lesions confirmed the diagnosis of bullous pemphigoid, and she had prompt clinical resolution with systemic tetracycline and steroids.

Keywords

Vulvar cancer; Radiation dermatitis; Bullous pemphigoid

Cite and Share

S. K. Parikh,A. Ravi,D. Yi-Shin Kuo,D. Nori. Bullous pemphigoid masquerading as acute radiation dermatitis: Case report. European Journal of Gynaecological Oncology. 2001. 22(5);322-324.

References

[1] Venning V. A., Wojnarowska F.: "The association of bullous pemphigoid and malignant disease: a case-control study''. Br. J Dermatol., 1990, 123, 439.

[2] Folliero G., Zurlo A.,A manti C., Tombolini V., DiPaola M: "Bullous pemphigoid induced by radiation therapy". Clin. Oncol (R. Coll. Radio!.), 1995, 7(4), 266.

[3] Duschet P., Schwarz T., Gschnait F.: "Bullous pemphigoid after radiation therapy". J. Am. Acad. Dermatol., 1988, 18, 441.

[4] Bernhardt M.: "Bullous pernphigoid after irradiation therapy". J Am. Acad. Dermatol., 1989, 20, 141.

[5] Sheerin N., Bourke J. F., Holder J., North J., Burns D. A.: "Bullous pernphigoid following radiotherapy". Clinical and Experimental Dermatolof?y, 1995, 20, 80.

[6] Jappe U., Bonnekoh B., Gollnick H.: "Guess what! Initially localized bullous pemphigoid at the irradiation site of breast carcinoma". Eur. J. Dermatol., 1999, 9(2), 139.

[7] Furukawa F., Osaki M., Imamura S., Hirose S.: "Bullous pemphigoid associated with radiotherapy for esophageal carcinoma". Dermatologica, 1981, 161, 451.

[8] Clayton A. S., Angeloni V.: "Bullous pemphigoid in a previously irradiated site". Cutis, 1998, 61, 73.

[9] Stanley J. R., Woodley D. T., Katz S.: "Identification and partial characterization of pemphigoid antigen extracted from normal human skin". J. Invest. Dermatol., 1984, 82, 108.

[10] Goldberg D. J., Sabolinski M., Bystryn J.C.: "Regional variation in the expression of bullous pemphigoid antigen and location of lesions in bullous pemphigoid". J. Invest. Dermatol., 1984, 82, 326.

[11] Jordan R. E., Norby-McFarland J. M., Tappeiner G.: "The complement system in bullous pemphigoid. II. Immunofluorescence evidence for both classical and alternate pathway activation". Clin. Immunol. Immunopathol., 1973, 3, 302.

[12] Berk M.A., Lorincz A. L.: "The treatment of bullous pemphigoid with tetracycline and niacinamide". Arch. Dermatol.. 1986, 122, 670.

[13] Ernst T-M., Marsch W. Ch.: "Induktion cines lokalisierten Pemphigoids durch energiereiche Strahlen". Dermatologica, 1982. 164, 73.

[14] Callens A., Valiant L., Machet M. L.: "Localized atypical pemphigoid on lymphoedema following radiation therapy". Acta Derm Venereal. (Stockh), 1993, 73, 461.

[15] Low G. J., Keeling J. H.: "Ionizing radiation-induced pemphigus" Arch. Dermatol., 1990, 126, 1319.

[16] Zwann F. E.,J ansen J.,N oordijk E. M.: "Graft-versus-host disease limited to the area of irradiated skin". Lancet, 1980, 1, 1081.

[17] Yates V. M., King C. M., Dave V. K.: "Lichen sclerosus following radiation therapy". Arch. Dermatol., 1985, 121, 1044.

[18] Ackerman A. B.: "Superficial perivascular dermatitis". In: Ackerman A. B., ed. "Histologic Diagnosis of Inflammatory Skin Diseases". Philadelphia, Lea & Febiger, 1978, 169.

[19J Maurice P. D. L.,A llen B. R.,M arriott D. W.,P owell R. J.,R eeves W. G.: "Skin immunofluorescence in the diagnosis of primary bullous diseases: a review of 279 cases". Clin. Exp. Dermatol., 1986, 11, 352.

[20] Berk M. A., Lorincz A. L.: "The treatment of bullous pemphigoid with tetracycline and niacinamide". Arch. Dermatol.,1986, 122, 670.

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