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Recurrent Paget's disease of the vulva in a myocutaneous flap: Case report and review of the literature

  • W. A. Tjalma1,2,*,
  • I. D. Cooremans1
  • W. Jeuris3
  • E. A. Van Marck3
  • J.M. Monaghan1

1Division of Gynecologic Oncology, Antwerp University Hospital, Antwerp, Belgium

2Northern Gynecological Oncology Centre, Queen Elizabeth Hospital, Gateshead, UK.

3Department of Pathology, Antwerp University Hospital, Antwerp, Belgium

DOI: 10.12892/ejgo20010113 Vol.22,Issue 1,January 2001 pp.13-15

Published: 10 January 2001

*Corresponding Author(s): W. A. Tjalma E-mail:

Abstract

A 74-year-old patient with recurrent Paget's disease of the vulva in the gluteus maximus island myocutaneous flap 11 years after a hemivulvectomy with reconstruction is presented. This report is only the second case of recurrent noninvasive Paget's disease in a reconstructive flap. The English literature on this subject is reviewed with special attention to the biological behavior of these tumors.

Keywords

Paget; Vulva; Recurrence; Myocutaneous flap

Cite and Share

W. A. Tjalma,I. D. Cooremans,W. Jeuris,E. A. Van Marck,J.M. Monaghan. Recurrent Paget's disease of the vulva in a myocutaneous flap: Case report and review of the literature . European Journal of Gynaecological Oncology. 2001. 22(1);13-15.

References

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[2] Fanning J.,L ambert H. C.,H ale T. M.,M orris P. C.,S chuerch C.: "Paget's disease of the vulva: prevalence of associated vulvar adcnocarcinoma, invasive Paget's disease, and recurrence after surgical excision". Am. J. Ohstet. Gynecol., 1999, 180, 24.

[3] Scheistroen M.,T rope C., Kaern J.,P ettersen E. 0.,A lfsen G. C., Nesland J.M.: "DNA ploidy and expression of p53 and c-erbB-2 in extramammary Paget's disease of the vulva". Gynecol. Oncol., 1997, 64, 88.

[4] Creasman W.T .,G allager H. S.,R utledge F.: "Paget's disease of the vulva". Gynecol. Oncol., 1975, 3, 133.

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[7] Fishman D. A.. Chambers S. K., Schwartz P. E.. Kohorn E. I.. Chambers J. T.: "Extramammary Paget's disease of the vulva" Gvnecol. Oncol.. 1995, 56, 266.

[8] DiSaia P. J., Dorion G. E., Cappuccini F., Carpenter P. M.: "A report of two cases of recurent Paget's disease of the vulva in a split-thickness graft and its possible pathogenesis-labeled " retrodisemination". Gynecol. Oncol., 1995, 57, 109.

[9] Garzetti G. G., Bertani A.,T ranquilli A.L .,T iriduzzi M., Valensise H., Romanini C.: "Paget's disease of the vulva: advantage of demolitive surgery". Eur. J. Gynaecol. Oneal.,1992, 13, 74.

[10] Misas J. E.,L arson J. E.,P odczaki E.,M anetta A.. Mortel R.: "Recurrent Paget disease of the vulva in a split-thickness graft". Obstet. Gynecol., 1990, 76, 543.

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[12] de Jonge E.T., Knobel J.: "Recurrent Paget's disease of the vulva after simple vulvectomy and skin grafting. A case report". S. Afr. Med. J., 1988, 73, 46.

[13] Geisler J.P.,S towell M. J.. Melton M.E .,M aloney C.D .,Geisler H. E.: "Extramammary Paget's disease of the vulva recurring in a skin graft". Gynecol. Oncol., 1995, 56, 446.

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