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DNA polymorphism analysis of a pure non-gestational choriocarcinoma of the ovary: case report

  • T. Shigematsu1,*,
  • T. Kamura2
  • T. Arima3
  • N. Wake3
  • H. Nakano1

1Department of Gynecology and Obstetrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan

2Department of Obstetrics and Gynecology, Kurume University Hospital, Kurume, Japan

3Department of Reproductive Physiology and Endocrinology, the Institute of Bioregulation, Kyushu University, Oita, Japan

DOI: 10.12892/ejgo200002153 Vol.21,Issue 2,March 2000 pp.153-154

Published: 10 March 2000

*Corresponding Author(s): T. Shigematsu E-mail:

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Abstract

A 45-year-old nulligravida woman died from carcinoma peritonitis with choriocarcinoma arising in the ovary. This tumor was resistant to chemotherapy after debulking surgery. DNA polymorphism analysis was useful in proving the choriocarcinoma to be non-gestational carcinoma. In this paper, the clinical course and DNA polymorphism findings are mainly discussed.

Keywords

Ovary; Choriocarcinoma; Non-gestational origin; DNA polymorphism analysis

Cite and Share

T. Shigematsu,T. Kamura,T. Arima,N. Wake,H. Nakano. DNA polymorphism analysis of a pure non-gestational choriocarcinoma of the ovary: case report. European Journal of Gynaecological Oncology. 2000. 21(2);153-154.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200002153

References

[1] Arima T., Imamura T., Sakuragi N., Higashi M., Kamura T., Fujmoto S. et al.: "Malignant trophoblastic neoplasms with diffe­rent modes of origin". Cancer Genet. Cytogenet., 1995, 85, 5.

[2] Arima T., Imamura T., Amada S., Tsuneyoshi M., Wake N.: "Genetic origin of malignant trophoblastic neoplasms". Cancer Genet. Cytogenet., 1994, 73, 95.

[3] Kidd K. K., Klingler H.P., Ruddle F. H.: "Human gene mappmg 11". Cytogenet. Cell Genet., 1991, 51, 1.

[4] Vance R. P., Geisinger K. R.: "Pure nongestational choriocarci-noma of the ovary. Report of a case". Cancer, 1985, 56, 2321.

[5] Jacobs A. J., Newland J. R., Green R. K.: "Pure choriocarcinoma of the ovary". Obstet. Gynecol. Surv., 1982, 37, 603.

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