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Megestrol-induced clinical adrenal insufficiency

  • A. Goodman1,*,
  • E. Cagliero2

1Assistant Professor of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School Massachusetts General Hospital, USA

2Assistant Professor of Medicine, Harvard Medical School, Boston, USA

DOI: 10.12892/ejgo200002117 Vol.21,Issue 2,March 2000 pp.117-118

Published: 10 March 2000

*Corresponding Author(s): A. Goodman E-mail:

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Abstract

Objective: To describe a case of megestrol-induced adrenal insufficiency.

Methods: A patient who received megestrol and then developed pituitary-adrenal axis abnormalities is described. The literature is reviewed.

Results: The patient developed megestrol-induced Cushingoid features. She developed adrenal insufficiency when megestrol was stopped.

Conclusion: Megestrol can induce alterations of the pituitary-adrenal axis in some patients. It is important to consider a diagnosis of adrenal insufficiency in patients with symptoms of fatigue, hypotension, and asthenia who have been treated with megestrol.

Keywords

Megestrol; Adrenal insufficiency; Cushingoid Features

Cite and Share

A. Goodman,E. Cagliero. Megestrol-induced clinical adrenal insufficiency. European Journal of Gynaecological Oncology. 2000. 21(2);117-118.

URL:

https://www.ejgo.net/articles/10.12892/ejgo200002117

References

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